Suppr超能文献

自闭症:一种跨诊断、维度、推理的建构?

Autism: a transdiagnostic, dimensional, construct of reasoning?

机构信息

Department of Child and Adolescent Psychiatry, Psychiatry Region Zealand, Ny Østergade 12, DK-4000, Roskilde, Denmark.

Faculty of Medical and Health Sciences, Department of Clinical Medicine, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen N, Denmark.

出版信息

Eur J Neurosci. 2018 Mar;47(6):515-533. doi: 10.1111/ejn.13599. Epub 2017 May 25.

Abstract

The concept of autism has changed across time, from the Bleulerian concept, which defined it as one of several symptoms of dementia praecox, to the present-day concept representing a pervasive development disorder. The present theoretical contribution to this special issue of EJN on autism introduces new theoretical ideas and discusses them in light of selected prior theories, clinical examples, and recent empirical evidence. The overall aim is to identify some present challenges of diagnostic practice and autism research and to suggest new pathways that may help direct future research. Future research must agree on the definitions of core concepts such as autism and psychosis. A possible redefinition of the concept of autism may be a condition in which the rationale of an individual's behaviour differs qualitatively from that of the social environment due to characteristic cognitive impairments affecting reasoning. A broad concept of psychosis could focus on deviances in the experience of reality resulting from impairments of reasoning. In this light and consistent with recent empirical evidence, it may be appropriate to redefine dementia praecox as a developmental disorder of reasoning. A future challenge of autism research may be to develop theoretical models that can account for the impact of complex processes acting at the social level in addition to complex neurobiological and psychological processes. Such models could profit from a distinction among processes related to (i) basic susceptibility, (ii) adaptive processes and (iii) decompensating factors involved in the development of manifest illness.

摘要

自闭症的概念随着时间的推移发生了变化,从 Bleuler 提出的概念,即自闭症是早发性痴呆的几种症状之一,到现在代表一种普遍发育障碍的概念。本理论贡献旨在为 EJN 自闭症特刊引入新的理论观点,并结合选定的先前理论、临床实例和最近的实证证据进行讨论。总体目标是确定诊断实践和自闭症研究的一些当前挑战,并提出可能有助于指导未来研究的新途径。未来的研究必须就自闭症和精神病等核心概念的定义达成一致。自闭症概念的重新定义可能是一种由于影响推理的特征性认知障碍,导致个体行为的合理性与其所处的社会环境在质上存在差异的状态。精神病的广泛概念可以集中在由于推理障碍导致的对现实体验的偏差上。从这个角度来看,并与最近的实证证据一致,将早发性痴呆重新定义为推理发育障碍可能是合适的。自闭症研究的未来挑战之一可能是开发能够解释除复杂神经生物学和心理学过程之外,在社会层面上发挥作用的复杂过程的理论模型。这些模型可以从与(i)基本易感性、(ii)适应性过程和(iii)与明显疾病发展相关的代偿因素相关的过程中获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de1e/6084350/fbefeac731b9/EJN-47-515-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验