Shanb Alsayed Abdelhameed, Youssef Enas Fawzy, Muaidi Qassim Ibrahim, Alothman Abdullah Ahmed
Department of Physical Therapy, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Alkhobar, Dammam City, KSA.
Chairman of Physical Therapy Department, Imam Abdulrahman Bin Faisal University, Alkhobar, Dammam City, KSA.
J Back Musculoskelet Rehabil. 2017 Aug 3;30(4):903-912. doi: 10.3233/BMR-160607.
Osteoporosis usually develops gradually and progresses without significant signs and symptoms. It is one of the most common musculoskeletal conditions associated with aging.
To evaluate the effects of whole body vibration (WBV) or magnetic therapy in addition to standard pharmacological treatment on bone mineral density (BMD) in elderly individuals being treated for osteoporosis.
Eighty-five participants, 60-75 years of age, were randomly divided into three groups. All three groups received the same standard pharmacological treatment comprised of vitamin D, calcium, and alendronate sodium. In Group I, thirty participants were also exposed to WBV for 25 minutes in each session with two sessions per week for 4 months. In Group II, thirty participants were exposed to magnetic therapy for 50 minutes in each session with two sessions per week for 4 months. In Group III, twenty-five participants received only pharmacological treatment. Dual-energy X-ray absorptiometry was used to measure BMD of the lumbar spine and femoral heads before and after interventions. Venus blood sample was drawn for analysis of calcium and vitamin D.
An ANOVA test detected significant (p< 0.05) differences in BMD after treatment among the three groups with no significant difference was detected between patients receiving WBV and magnetic therapy. Statistical t-tests detected significant (p< 0.05) increases in BMD after application of WBV or magnetic therapy in combination with pharmacological treatment, but no significant increase after pharmacological treatment alone.
Addition of either WBV or magnetic therapy to standard pharmacological treatment for osteoporosis significantly increased BMD in elderly subjects. No significant difference in effectiveness was detected between these two alternative therapy modalities. Consequently, either WBV or magnetic therapy could be effectively applied in conjunction with pharmacological treatment to increase BMD in elderly osteoporotic patients.
骨质疏松症通常逐渐发展,进展过程中无明显体征和症状。它是与衰老相关的最常见肌肉骨骼疾病之一。
评估在接受骨质疏松症治疗的老年人中,除标准药物治疗外,全身振动(WBV)或磁疗对骨密度(BMD)的影响。
85名年龄在60 - 75岁的参与者被随机分为三组。所有三组均接受相同的标准药物治疗,包括维生素D、钙和阿仑膦酸钠。第一组30名参与者还每周接受两次全身振动,每次25分钟,共4个月。第二组30名参与者每周接受两次磁疗,每次50分钟,共4个月。第三组25名参与者仅接受药物治疗。干预前后采用双能X线吸收法测量腰椎和股骨头的骨密度。采集静脉血样分析钙和维生素D。
方差分析检测到三组治疗后骨密度存在显著差异(p < 0.05),接受全身振动和磁疗的患者之间无显著差异。统计学t检验检测到全身振动或磁疗联合药物治疗后骨密度显著增加(p < 0.05),但单独药物治疗后无显著增加。
在骨质疏松症的标准药物治疗中添加全身振动或磁疗可显著提高老年受试者的骨密度。这两种替代治疗方式在有效性上无显著差异。因此,全身振动或磁疗均可有效地与药物治疗联合应用,以提高老年骨质疏松症患者的骨密度。