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参与黑腹果蝇I-R杂种不育的I因子的结构与基因组组织

Structure and genomic organization of I elements involved in I-R hybrid dysgenesis in Drosophila melanogaster.

作者信息

Crozatier M, Vaury C, Busseau I, Pelisson A, Bucheton A

机构信息

Unité Associée au CNRS no. 360, Université Blaise Pascal, Aubière, France.

出版信息

Nucleic Acids Res. 1988 Oct 11;16(19):9199-213. doi: 10.1093/nar/16.19.9199.

DOI:10.1093/nar/16.19.9199
PMID:2845368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC338701/
Abstract

I-R hybrid dysgenesis in D. melanogaster is controlled by transposable elements known as I factors which terminate at their 3' ends by an A-rich sequence. Inducer strains contain active I factors. Both reactive and inducer stocks possess defective I elements. We have cloned various I elements from both categories of strains. The I elements having recently transposed in inducer strains have a structure closely related to that of active I factors. However we have isolated one such I element that is truncated at its 5' end. The I elements common to reactive and inducer strains are affected by various rearrangements and many point mutations. They do not appear to be simple derivatives of complete I factors.

摘要

黑腹果蝇中的I-R杂种不育现象由一种称为I因子的转座元件控制,这些I因子在其3'末端以富含A的序列终止。诱导品系含有活性I因子。反应品系和诱导品系都具有缺陷型I元件。我们已经从这两类品系中克隆了各种I元件。最近在诱导品系中转座的I元件具有与活性I因子密切相关的结构。然而,我们分离出了一个这样的I元件,它在其5'末端被截断。反应品系和诱导品系共有的I元件受到各种重排和许多点突变的影响。它们似乎不是完整I因子的简单衍生物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4d2/338701/9332debd28e2/nar00161-0137-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4d2/338701/630ea2734a28/nar00161-0134-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4d2/338701/9332debd28e2/nar00161-0137-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4d2/338701/630ea2734a28/nar00161-0134-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4d2/338701/9332debd28e2/nar00161-0137-a.jpg

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