Panova Ina G, Yakovleva Marina A, Tatikolov Alexander S, Kononikhin A S, Feldman Tatiana B, Poltavtseva Rimma A, Nikolaev E N, Sukhikh Gennady T, Ostrovsky Mikhail A
Koltsov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow 119334, Russia.
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow 119334, Russia.
Exp Eye Res. 2017 Jul;160:31-37. doi: 10.1016/j.exer.2017.04.008. Epub 2017 Apr 25.
The presence of carotenoids in the vitreous body, retina, lens, retinal pigment epithelium together with choroid (hereinafter RPE), and ciliary body and iris together with choroidal stroma (hereinafter CBI) was studied throughout the second trimester of prenatal development of the human eye. It has been found that the vitreous body, retina, and RPE contain lutein and its oxidized forms. Zeaxanthin was not found in the tissues studied. The presence of lutein in the vitreous body is transient and no longer detected after 28 weeks of gestation. Lutein was not detected in the lens and CBI, but its oxidized forms were found. The presence of carotenoids in different tissues of the eye in the course of normal eye development and the antioxidant role of carotenoids are discussed.
在人眼产前发育的第二个孕期，对玻璃体、视网膜、晶状体、视网膜色素上皮连同脉络膜（以下简称RPE）以及睫状体和虹膜连同脉络膜基质（以下简称CBI）中类胡萝卜素的存在情况进行了研究。已发现玻璃体、视网膜和RPE含有叶黄素及其氧化形式。在所研究的组织中未发现玉米黄质。玻璃体中叶黄素的存在是短暂的，在妊娠28周后不再检测到。在晶状体和CBI中未检测到叶黄素，但发现了其氧化形式。讨论了正常眼睛发育过程中眼睛不同组织中类胡萝卜素的存在情况以及类胡萝卜素的抗氧化作用。
