[产前发育期间人眼玻璃体内类胡萝卜素的检测]

[Detection of carotenoids in the vitreous body of the human eye during prenatal development].

作者信息

Iakovleva M A, Panova I G, Fel'dman T B, Zak P P, Tatikolov A S, Sukhikh G T, Ostrovskiĭ M A

出版信息

Ontogenez. 2007 Sep-Oct;38(5):380-5.

Abstract

Carotenoids were found for the first time in the vitreous body of human eye during the fetal period from week 15 until week 28. Their maximum content was timed to week 16-22. No carotenoids were found the vitreous body of 31-week fetuses, as well as adult humans, which corresponds to the published data. It was shown using HPLC that chromatographic characteristics of these carotenoids correspond to those of lutein and zeaxanthin, characteristic pigments of the retinal yellow macula.

摘要

在孕期第15周直至第28周的胎儿期，首次在人眼玻璃体中发现类胡萝卜素。其最大含量出现在第16 - 22周。在31周胎儿以及成年人的玻璃体中未发现类胡萝卜素，这与已发表的数据相符。使用高效液相色谱法（HPLC）表明，这些类胡萝卜素的色谱特征与叶黄素和玉米黄质的特征相符，叶黄素和玉米黄质是视网膜黄斑的特征色素。