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动脉周围注射罂粟碱治疗机器人辅助腹腔镜肾部分切除术中的肾动脉痉挛。

Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy.

作者信息

Sorokin Igor, Stevens Sharnae L, Cadeddu Jeffrey A

机构信息

Department of Urology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA.

Department of Pharmacy, Baylor University Medical Center, Dallas, TX, USA.

出版信息

J Robot Surg. 2018 Mar;12(1):189-191. doi: 10.1007/s11701-017-0710-4. Epub 2017 Apr 28.

DOI:10.1007/s11701-017-0710-4
PMID:28455799
Abstract

Renal artery vasospasm can be a troublesome complication during robot-assisted laparoscopic partial nephrectomy. Urologists performing this procedure, especially if utilizing selective arterial vascular microdissection, should be aware of using papaverine for both prevention and treatment of renal artery vasospasm. We present a 33-year-old male who developed severe renal artery vasospasm just with hilar dissection causing the kidney to become ischemic. Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney. Our objective of this report is to raise awareness of this complication as well as to review the literature on periarterial papaverine use and the dosing for topical applications.

摘要

肾动脉痉挛可能是机器人辅助腹腔镜肾部分切除术期间一个棘手的并发症。实施该手术的泌尿外科医生,尤其是在采用选择性动脉血管显微解剖时,应知晓使用罂粟碱来预防和治疗肾动脉痉挛。我们报告一名33岁男性,其仅在肾门解剖时就发生了严重的肾动脉痉挛,导致肾脏缺血。将罂粟碱局部应用于肾动脉,结果使肾脏血管扩张并实现再灌注。本报告的目的是提高对这一并发症的认识,并回顾有关动脉周围使用罂粟碱及局部应用剂量的文献。

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本文引用的文献

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Zero ischemia anatomical partial nephrectomy: a novel approach.零缺血解剖性部分肾切除术:一种新方法。
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Self-retaining barbed suture for parenchymal repair during minimally invasive partial nephrectomy.微创部分肾切除术期间用于实质修复的自固定倒刺缝线。
J Endourol. 2011 Aug;25(8):1245-7; discussion 1247-8. doi: 10.1089/end.2011.0105. Epub 2011 Jul 11.
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Periarterial papaverine improves early postoperative renal function after retroperitoneoscopic partial nephrectomy.罂粟碱在腹膜后腹腔镜部分肾切除术后改善早期肾功能。
World J Urol. 2013 Aug;31(4):829-33. doi: 10.1007/s00345-011-0712-1. Epub 2011 Jun 17.
10
Periarterial application of papaverine during laparoscopic donor nephrectomy improves early graft function after kidney transplantation in pigs.
Surg Endosc. 2004 Mar;18(3):417-20. doi: 10.1007/s00464-003-8912-4. Epub 2004 Feb 2.