Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI 48202, USA.
Int Braz J Urol. 2013 May-Jun;39(3):377-86. doi: 10.1590/S1677-5538.IBJU.2013.03.11.
To examine the effect of surgical approach on perioperative morbidity and mortality after partial nephrectomy.
Within the Nationwide Inpatient Sample, patients who underwent RAPN or LPN between October 2008 and December 2009 were identified. Propensity-based matching was performed to adjust for potential baseline differences between the two groups. The rates of intraoperative and postoperative complications, blood transfusions, prolonged length of stay, and in-hospital mortality, stratified according to RAPN vs. LPN, were compared.
Overall, 851 (72.5%) patients underwent RAPN and 323 (27.5%) underwent LPN. For RAPN and LPN respectively, the following rates were recorded in the propensity-score matched cohort: blood transfusions, 4.5 vs. 6.8% (p = 0.223); intraoperative complications, 5.2 vs. 2.6% (p = 0.096); postoperative complications, 10.6 vs. 13.5% (p = 0.268); prolonged length of stay, 6.8 vs. 9.4% (p = 0.238); in-hospital mortality, 0.0 vs. 0.0%.
RAPN has supplanted LPN as the predominant minimally invasive surgical approach for renal masses. Perioperative outcomes after RAPN and LPN are comparable. Interpretation of these findings needs to take into account the lack of adjustment for case complexity and surgical expertise.
探讨部分肾切除术围手术期发病率和死亡率的手术入路的影响。
在全国住院患者样本中,确定了 2008 年 10 月至 2009 年 12 月期间接受 RAPN 或 LPN 的患者。进行基于倾向的匹配以调整两组之间潜在的基线差异。比较根据 RAPN 与 LPN 分层的术中并发症和术后并发症、输血、延长住院时间和住院死亡率的发生率。
共有 851 例(72.5%)患者接受 RAPN,323 例(27.5%)患者接受 LPN。对于 RAPN 和 LPN,分别在倾向评分匹配队列中记录了以下比率:输血,4.5%对 6.8%(p=0.223);术中并发症,5.2%对 2.6%(p=0.096);术后并发症,10.6%对 13.5%(p=0.268);延长住院时间,6.8%对 9.4%(p=0.238);住院死亡率,0.0%对 0.0%。
RAPN 已取代 LPN 成为肾肿瘤的主要微创外科方法。RAPN 和 LPN 的围手术期结果相当。这些发现的解释需要考虑到缺乏对病例复杂性和手术专业知识的调整。