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作为电休克治疗并发症的精神病性症状——一例报告

Psychotic symptoms as a complication of electroconvulsive therapy - a case report.

作者信息

Antosik-Wójcińska Anna, Chojnacka Magdalena, Święcicki Łukasz

机构信息

Oddział Chorób Afektywnych, II Klinika Psychiatryczna IPiN w Warszawie.

出版信息

Psychiatr Pol. 2017 Feb 26;51(1):23-27. doi: 10.12740/PP/62983.

Abstract

We report a patient who experienced atypical symptoms in the course of electroconvulsive therapy (ECT). During ECT treatment patient experienced psychotic symptoms which should be differentiated with prolonged delirium and nonconvulsive status epilepticus. 46-year-old female was referred to hospital with a diagnosis of major depressive disorder with no psychotic features in the course of recurrent depression. Despite several changes of pharmacological treatment no improvement was achieved, therefore it was decided to initiate ECT. Physical and neurological examination revealed no deviations from the norm. The results of other tests (CT and EEG) were normal. 4 bilateral, bitemporal ECT procedures were performed. The course of each procedure was typical, the same doses of anesthetic medication and pulse dose was administered throughout all of the procedures. The duration of seizure was 32-40 s. Despite this mental symptoms observed during the course of the treatment differed from known to the authors from both their own experience and from literature. Delusions of reference, persecution, agitation, oneiric delusions and olfactory hallucinations which appeared after the 4th ECT session maintained for 14 days and resolved after treatment with olanzapine. To the best of our knowledge, this is the first report on delusions of reference and persecution, oneiric delusions and olfactory hallucinations associated with the course of ECT.

摘要

我们报告了一名在电休克治疗(ECT)过程中出现非典型症状的患者。在ECT治疗期间,患者出现了精神病性症状,这些症状应与持续性谵妄和非惊厥性癫痫持续状态相鉴别。一名46岁女性因复发性抑郁症被转诊至医院,诊断为无精神病性特征的重度抑郁症。尽管多次改变药物治疗方案,但病情并无改善,因此决定开始ECT治疗。体格检查和神经系统检查未发现异常。其他检查(CT和脑电图)结果正常。进行了4次双侧颞部ECT治疗。每次治疗过程均典型,所有治疗过程中使用的麻醉药物剂量和脉冲剂量相同。癫痫发作持续时间为32 - 40秒。尽管如此,治疗过程中观察到的精神症状与作者根据自身经验和文献所知的情况不同。在第4次ECT治疗后出现的牵连观念、被害妄想、激越、梦样妄想和幻嗅持续了14天,在使用奥氮平治疗后缓解。据我们所知,这是关于与ECT过程相关的牵连观念和被害妄想、梦样妄想和幻嗅的首例报告。

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