Medicine, Western University, London, Ontario, Canada
Ophthalmology, Western University, London, Ontario, Canada.
BMJ Case Rep. 2022 Mar 22;15(3):e248565. doi: 10.1136/bcr-2021-248565.
A female geriatric patient with major depressive disorder, current episode severe, received eight right unilateral electroconvulsive therapy (ECT) treatments over the course of 3 weeks. After her third treatment, she began experiencing brief visual hallucinations, each lasting less than 5 s, consisting of dark to grey coloured, poorly defined geometric shapes and objects. These episodes occurred only during the day with no change in consciousness. With each additional treatment, the episodes increased in frequency, reaching a crescendo of approximately 20 episodes per day. After terminating ECT, the frequency of these episodes decreased and then ceased 6 weeks later. Neuroimaging and ophthalmological investigations discounted a space occupying lesion or vision loss. This case demonstrates a close temporal relationship between ECT and new onset visual hallucinations. Clinicians should be aware of the possibility that elderly depressed patients may develop visual hallucinations during a course of ECT.
一位患有重度抑郁症的老年女性患者,当前发作严重,在 3 周的时间内接受了 8 次右侧单侧电惊厥疗法(ECT)治疗。在她的第三次治疗后,她开始出现短暂的视觉幻觉,每次持续不到 5 秒,包括暗到灰色的、定义不清的几何形状和物体。这些发作仅在白天发生,意识没有变化。随着每次额外的治疗,发作的频率增加,达到每天约 20 次的高潮。ECT 治疗结束后,这些发作的频率减少,6 周后停止。神经影像学和眼科检查排除了占位性病变或视力丧失。这个病例表明 ECT 和新出现的视觉幻觉之间存在密切的时间关系。临床医生应该意识到老年抑郁患者在接受 ECT 治疗过程中可能会出现视觉幻觉。