Rai Sakshi, Mishra Biswa Ranjan, Sarkar Sukanto, Praharaj Samir Kumar, Das Sudipta, Maiti Rituparna, Agrawal Nidhi, Nizami S Haque
Department of Clinical Psychology, Central Institute of Psychiatry, Kanke, Ranchi, Jharkhand, 834006, India.
Department of Psychiatry, AIIMS, Bhubaneswar, Bhubaneswar, Odisha, 751019, India.
Community Ment Health J. 2018 Feb;54(2):218-223. doi: 10.1007/s10597-017-0139-2. Epub 2017 Apr 29.
To study the association of impulsivity, high-risk behaviours and incidence of HIV infection in patients with alcohol dependence and bipolar mania. This was a cross-sectional hospital-based pilot study and the sample consisted of male patients divided into three groups: 25 patients with alcohol dependence and 25 with bipolar mania as per ICD-10 Diagnostic Criteria for Research and 25 normal controls. Severity of Alcohol Dependence Questionnaire (SADQ) and Young Mania Rating Scale (YMRS) were administered on alcohol dependent and bipolar patients, respectively. All three groups were rated on Barrett's Impulsivity Scale (BIS) and HIV Risk-taking Behaviour Scale (HRBS). None of the patients tested positive for either HIV 1 or 2. BIS motor impulsivity, BIS total score and HRBS total score were significantly higher in alcohol dependent patients as compared to bipolar mania patients. In the Alcohol dependent group, BIS score significantly correlated with education years, age of onset of alcohol use and SADQ, whereas, HRBS total score significantly correlated with SADQ scores. In the bipolar mania group, BIS significantly correlated with YMRS, and total number of episodes, whereas, there was no significant correlation of HRBS total score with any clinical variable. The findings of this pilot study underscore the link between alcohol use disorder and the impulsive behaviours that can lead to HIV infection, and highlight that those risks are higher for individuals with alcohol dependency than for individuals with bipolar disorder.
研究酒精依赖和双相躁狂患者的冲动性、高危行为与艾滋病毒感染发生率之间的关联。这是一项基于医院的横断面试点研究，样本包括男性患者，分为三组：根据ICD - 10研究诊断标准，25例酒精依赖患者、25例双相躁狂患者和25例正常对照者。分别对酒精依赖患者和双相情感障碍患者进行酒精依赖严重程度问卷（SADQ）和青年躁狂评定量表（YMRS）评估。所有三组均采用巴雷特冲动性量表（BIS）和艾滋病毒冒险行为量表（HRBS）进行评分。所有患者的HIV - 1或HIV - 2检测均为阴性。与双相躁狂患者相比，酒精依赖患者的BIS运动冲动性、BIS总分和HRBS总分显著更高。在酒精依赖组中，BIS评分与受教育年限、开始饮酒年龄和SADQ显著相关，而HRBS总分与SADQ评分显著相关。在双相躁狂组中，BIS与YMRS以及发作总次数显著相关，而HRBS总分与任何临床变量均无显著相关性。这项试点研究的结果强调了酒精使用障碍与可能导致艾滋病毒感染的冲动行为之间的联系，并突出表明，酒精依赖个体比双相情感障碍个体面临的这些风险更高。
