Centre for Addiction and Mental Health, Toronto, ON, M5S 2S1, Canada.
AIDS Behav. 2009 Dec;13(6):1021-36. doi: 10.1007/s10461-009-9589-z. Epub 2009 Jul 18.
The present investigation attempted to quantify the relationship between alcohol consumption and unprotected sexual behavior among people living with HIV/AIDS (PLWHA). A comprehensive search of the literature was performed to identify key studies on alcohol and sexual risk behavior among PLWHA, and three separate meta-analyses were conducted to examine associations between unprotected sex and (1) any alcohol consumption, (2) problematic drinking, and (3) alcohol use in sexual contexts. Based on 27 relevant studies, meta-analyses demonstrated that any alcohol consumption (OR = 1.63, CI = 1.39-1.91), problematic drinking (OR = 1.69, CI = 1.45-1.97), and alcohol use in sexual contexts (OR = 1.98, CI = 1.63-2.39) were all found to be significantly associated with unprotected sex among PLWHA. Taken together, these results suggest that there is a significant link between PLWHA's use of alcohol and their engagement in high-risk sexual behavior. These findings have implications for the development of interventions to reduce HIV transmission risk behavior in this population.
本研究旨在定量评估 HIV/AIDS 感染者（PLWHA）中饮酒与无保护性行为之间的关系。通过全面检索文献，确定了关于 PLWHA 饮酒与性风险行为的关键研究，并进行了三项独立的荟萃分析，以检验无保护性行为与（1）任何饮酒、（2）问题性饮酒和（3）性行为中饮酒之间的关联。基于 27 项相关研究，荟萃分析表明，任何饮酒（OR = 1.63，CI = 1.39-1.91）、问题性饮酒（OR = 1.69，CI = 1.45-1.97）和性行为中的饮酒（OR = 1.98，CI = 1.63-2.39）均与 PLWHA 中的无保护性行为显著相关。综上所述，这些结果表明，PLWHA 饮酒与高危性行为之间存在显著关联。这些发现对于制定干预措施以降低该人群中的 HIV 传播风险行为具有重要意义。
