McPherson Laura, Basu Mohua, Gander Jennifer, Pastan Stephen O, Mohan Sumit, Wolf Michael S, Chiles Mariana, Russell Allison, Lipford Kristie, Patzer Rachel E
Division of Transplantation, Department of Surgery, Emory University School of Medicine, Atlanta, GA, USA.
Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Clin Transplant. 2017 Jul;31(7). doi: 10.1111/ctr.12991. Epub 2017 May 29.
Although kidney transplantation provides a significant benefit over dialysis, many patients with end-stage renal disease (ESRD) are conflicted about their decision to undergo kidney transplant. We aimed to identify the prevalence and characteristics associated with decisional conflict between treatment options in ESRD patients presenting for transplant evaluation. Among a cross-sectional sample of patients with ESRD (n=464) surveyed in 2014 and 2015, we assessed decisional conflict through a validated 10-item questionnaire. Decisional conflict was dichotomized into no decisional conflict (score=0) and any decisional conflict (score>0). We investigated potential characteristics of patients with decisional conflict using bivariate and multivariable logistic regression. The overall mean age was 50.6 years, with 62% male patients and 48% African American patients. Nearly half (48.5%) of patients had decisional conflict regarding treatment options. Characteristics significantly associated with decisional conflict in multivariable analysis included male sex, lower educational attainment, and less transplant knowledge. Understanding characteristics associated with decisional conflict in patients with ESRD could help identify patients who may benefit from targeted interventions to help patients make informed, value-based, and supported decisions when deciding how to best treat their kidney disease.
尽管肾移植比透析有显著优势,但许多终末期肾病(ESRD)患者对接受肾移植的决定仍存在矛盾心理。我们旨在确定在接受移植评估的ESRD患者中,治疗选择之间决策冲突的患病率及相关特征。在2014年和2015年调查的ESRD患者横断面样本(n = 464)中,我们通过一份经过验证的10项问卷评估决策冲突。决策冲突被分为无决策冲突(得分=0)和有任何决策冲突(得分>0)。我们使用双变量和多变量逻辑回归研究有决策冲突患者的潜在特征。总体平均年龄为50.6岁,男性患者占62%,非裔美国患者占48%。近一半(48.5%)的患者在治疗选择上存在决策冲突。多变量分析中与决策冲突显著相关的特征包括男性、教育程度较低和移植知识较少。了解ESRD患者决策冲突的相关特征有助于识别那些可能从针对性干预中受益的患者,以帮助他们在决定如何最佳治疗肾病时做出明智、基于价值观且得到支持的决策。