Deshwal Rajesh, Tiwari Dhirendra, Singh Raj
Consultant in Internal Medicine and HIV Medicine.
Medical Officer.
J Assoc Physicians India. 2017 Feb;65(2):57-61.
The purpose of this study was to assess the clinical profile, biochemical parameters and outcome in a series of 78 patients of heat stroke admitted and treated in a military hospital in India.
This was a prospective study in a military hospital. A total of 78 patients of exertional heat stroke admitted and treated over more than 2 years are reported. Cooling measures started immediately on site of occurrence, carried on during evacuation and in hospital, IV normal saline initiated, clinical symptoms and signs were noted. Blood was collected and sent for hematological, biochemical and coagulation parameters.
Clinical features noted were violent behavior( 20.51%), confusional state (58.97%),coma (29.48%), seizure (33.33%),and vomiting (26.92%).Vital parameters were recorded and laboratory parameters revealed hypophosphatemia, hyponatremia, hypokalemia along with raised transaminases, creatinine kinase and lactic dehydrogenase. Patients were managed with cooling measures, IV fluids and supportive measures. All of them survived to be discharged in a mean of 8.34 days.
Timely diagnosis, prompt intervention in form of effective cooling measures to reduce the temperature to acceptable levels within 30 mins, volume resuscitation, judicious use of ionotropes after adequate volume replacement and effective supportive care resulted in a favourable outcome.
本研究旨在评估印度一家军队医院收治的78例中暑患者的临床特征、生化参数及预后情况。
这是一项在军队医院开展的前瞻性研究。报告了2年多来收治并治疗的78例劳力性中暑患者。在中暑发生现场立即开始降温措施,并在转运及住院期间持续进行,同时静脉输注生理盐水,记录临床症状和体征。采集血液并送检血液学、生化及凝血参数。
观察到的临床特征包括暴力行为(20.51%)、意识模糊状态(58.97%)、昏迷(29.48%)、癫痫发作(33.33%)及呕吐(26.92%)。记录了生命体征参数,实验室参数显示存在低磷血症、低钠血症、低钾血症,同时转氨酶、肌酸激酶及乳酸脱氢酶升高。对患者采取了降温措施、静脉补液及支持性措施进行治疗。所有患者均存活,平均8.34天后出院。
及时诊断,通过有效降温措施在30分钟内将体温降至可接受水平、进行容量复苏、在充分补液后合理使用血管活性药物以及有效的支持性护理等及时干预措施,取得了良好的预后效果。