Adebo O A, Osinowo O
Department of Surgery, University College Hospital, Ibadan, Nigeria.
Afr J Med Med Sci. 1988 Sep;17(3):145-8.
A retrospective study of 37 patients undergoing pulmonary resection, between 1975 and 1980, was performed to establish the incidence of wound infection and to determine contributory factors. Sixteen patients had suppurative lung disease while 11 had pulmonary tuberculosis. The majority of the patients received prophylactic antibiotic (Ampicillin and Cloxacillin) given intramuscularly or intravenously, prior to thoracotomy, and continued for several days post-operatively. Twenty of the 37 cases (54%) developed wound infection, defined as any purulent wound drainage in the post-operative period. The patients with infection (group A) did not differ from those without (group B) as regards presence of pyorrhoea or haemoptysis, the duration of operation or the quantity of blood infused during surgery. A significant difference in the duration of chest intubation was identified between group A (6 +/- 1.3 days) and group B (3 +/- 1.5 days) (P less than 0.001). The implication of the results towards the modification of post-operative management of patients is discussed.
对1975年至1980年间接受肺切除术的37例患者进行了一项回顾性研究，以确定伤口感染的发生率并确定相关因素。16例患者患有化脓性肺部疾病，11例患有肺结核。大多数患者在开胸手术前接受了预防性抗生素（氨苄青霉素和氯唑西林），通过肌肉注射或静脉注射给药，并在术后持续使用数天。37例病例中有20例（54%）发生了伤口感染，定义为术后任何脓性伤口引流。感染患者（A组）与未感染患者（B组）在是否存在脓性分泌物或咯血、手术持续时间或手术期间输注的血量方面没有差异。A组（6±1.3天）和B组（3±1.5天）之间的胸管插管持续时间存在显著差异（P<0.001）。讨论了这些结果对患者术后管理调整的意义。
