肾移植受者移植后1年的尿路感染
Urinary tract infections in kidney transplant recipients 1 year after transplantation.
作者信息
Shams Seyyede Fatemeh, Eidgahi Elham Shaarbaf, Lotfi Zahra, Khaledi Azad, Shakeri Sepideh, Sheikhi Maryam, Bahrami Afsane
机构信息
Kidney Transplantation Complication Research Center, School of Medicine, Montaserie Organ Transplantation Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Hematology and Blood Bank, Cancer Molecular Pathology Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
出版信息
J Res Med Sci. 2017 Feb 16;22:20. doi: 10.4103/1735-1995.200274. eCollection 2017.
BACKGROUND
One of the main causes of adverse complications following kidney transplantation is urinary tract infection (UTI). This study was done to define the incidence rate, clinical profiles, causative microorganisms, and UTI risk factors among kidney transplant recipients in Mashhad city.
MATERIALS AND METHODS
In this retrospective study, we perused medical files of 247 kidney recipients who underwent transplant surgery at Mashhad University Montaserie Hospital, during 2012-2014. All patients were followed for UTI during the 1 year after surgery.
RESULTS
75 episodes of UTI developed by 152 pathogens in 56 (22.7%) of patients during 1-year follow-up. 26.6% of total UTIs were diagnosed within the 1 month after transplantation. The most frequently isolated uropathogens were (55.3%, = 84). The high rate of candiduria (8.5%) was observed, too.
CONCLUSION
UTI is known as one of the hospitalization reasons in kidney transplantation recipients. Defining appropriate antibiotic prophylaxis against bacterial and fungal agents and early removal of urethral catheter are suggested to decrease posttransplantation complications.
背景
肾移植术后不良并发症的主要原因之一是尿路感染（UTI）。本研究旨在确定马什哈德市肾移植受者中UTI的发病率、临床特征、致病微生物及UTI危险因素。
材料与方法
在这项回顾性研究中，我们查阅了2012年至2014年期间在马什哈德大学蒙塔泽里医院接受移植手术的247例肾移植受者的病历。所有患者在术后1年内均接受UTI随访。
结果
在1年的随访期间，56例（22.7%）患者发生了75次UTI发作，由152种病原体引起。26.6%的UTI在移植后1个月内被诊断出来。最常分离出的尿路病原体是（55.3%，=84）。念珠菌尿的发生率也很高（8.5%）。
结论
UTI是肾移植受者住院的原因之一。建议确定针对细菌和真菌制剂的适当抗生素预防措施，并尽早拔除尿道导管，以减少移植后并发症。
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