• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

垂体性侏儒症的牙齿异常:一例报告及文献复习

Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature.

作者信息

Ferrante Franco, Blasi Sergio, Crippa Rolando, Angiero Francesca

机构信息

Department of Surgical Medical Sciences and Integrated Diagnostic, University of Genoa, Genoa, Italy.

出版信息

Case Rep Dent. 2017;2017:5849173. doi: 10.1155/2017/5849173. Epub 2017 Mar 28.

DOI:10.1155/2017/5849173
PMID:28458931
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5387821/
Abstract

Hypopituitarism is a disorder caused by a reduced level of trophic hormones that may be consequent on different destructive processes. The clinical manifestations depend on the type of hormone involved. A deficiency of growth hormone (GH) in children causes the lack of growth known as pituitary dwarfism. The case is reported of a patient with pituitary dwarfism, multiple dental anomalies, functional prosthetic problems, and a revision of the literature. She was subjected to prosthetic rehabilitation without surgical intervention, using zirconium substructures, thus eliminating the potential complications that may require trauma surgery. The therapeutic approach adopted led to excellent results and restored an aesthetic smile.

摘要

垂体功能减退症是一种由促激素水平降低引起的疾病,这可能是由不同的破坏性过程导致的。临床表现取决于所涉及的激素类型。儿童生长激素(GH)缺乏会导致生长不足,即垂体性侏儒症。本文报道了一例垂体性侏儒症患者,伴有多种牙齿异常、功能性修复问题,并对相关文献进行了综述。该患者在未进行手术干预的情况下,使用锆基底层结构进行了修复治疗,从而避免了可能需要创伤性手术的潜在并发症。所采用的治疗方法取得了极佳的效果,恢复了美观的笑容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/c7dc190223e6/CRID2017-5849173.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/2831eb0ec0d4/CRID2017-5849173.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/6db2e9b05ad6/CRID2017-5849173.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/60b7f8877763/CRID2017-5849173.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/c7dc190223e6/CRID2017-5849173.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/2831eb0ec0d4/CRID2017-5849173.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/6db2e9b05ad6/CRID2017-5849173.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/60b7f8877763/CRID2017-5849173.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/10ca/5387821/c7dc190223e6/CRID2017-5849173.004.jpg

相似文献

1
Dental Abnormalities in Pituitary Dwarfism: A Case Report and Review of the Literature.垂体性侏儒症的牙齿异常:一例报告及文献复习
Case Rep Dent. 2017;2017:5849173. doi: 10.1155/2017/5849173. Epub 2017 Mar 28.
2
Congenital hypopituitarism: clinico-radiological correlation.先天性垂体功能减退症:临床与放射学相关性
J Pediatr Endocrinol Metab. 2009 Oct;22(10):921-8. doi: 10.1515/jpem.2009.22.10.921.
3
GH and Pituitary Hormone Alterations After Traumatic Brain Injury.创伤性脑损伤后生长激素及垂体激素的变化
Prog Mol Biol Transl Sci. 2016;138:167-91. doi: 10.1016/bs.pmbts.2015.10.010. Epub 2015 Nov 4.
4
Growth Hormone Deficiency and Excessive Sleepiness: A Case Report and Review of the Literature.生长激素缺乏与过度嗜睡:一例病例报告及文献综述
Pediatr Endocrinol Rev. 2019 Sep;17(1):41-46. doi: 10.17458/per.vol17.2019.ge.ghdeficiencyandsleepiness.
5
Russell-Silver syndrome and hypopituitarism. Patient report and literature review.
Am J Dis Child. 1986 Feb;140(2):155-9. doi: 10.1001/archpedi.1986.02140160073037.
6
Hypopituitarism.垂体功能减退症
Pituitary. 2006;9(4):335-42. doi: 10.1007/s11102-006-0416-5.
7
Rare Frequency of Mutations in Pituitary Transcription Factor Genes in Combined Pituitary Hormone or Isolated Growth Hormone Deficiencies in Korea.韩国联合垂体激素缺乏症或孤立性生长激素缺乏症中垂体转录因子基因突变的罕见频率
Yonsei Med J. 2017 May;58(3):527-532. doi: 10.3349/ymj.2017.58.3.527.
8
Comparison of dental findings in patients with isolated growth hormone deficiency treated with human growth hormone (hGH) and in untreated patients with Laron-type dwarfism.接受人生长激素(hGH)治疗的孤立性生长激素缺乏症患者与未经治疗的拉伦型侏儒症患者的牙齿检查结果比较。
Oral Surg Oral Med Oral Pathol. 1988 Nov;66(5):581-6. doi: 10.1016/0030-4220(88)90379-9.
9
Pituitary gene mutations and the growth hormone pathway.垂体基因突变与生长激素通路
Semin Reprod Med. 2000;18(1):21-9. doi: 10.1055/s-2000-13473.
10
Relationship between the morphological evaluation of the pituitary and the growth hormone (GH) response to GH-releasing hormone Plus arginine in children and adults with congenital hypopituitarism.先天性垂体功能减退儿童及成人垂体形态学评估与生长激素(GH)对生长激素释放激素加精氨酸反应之间的关系。
J Clin Endocrinol Metab. 2001 Apr;86(4):1574-9. doi: 10.1210/jcem.86.4.7394.

引用本文的文献

1
A novel and complex chromosomal variation in a child with developmental delay: A case report.一名发育迟缓儿童的新型复杂染色体变异:病例报告。
Medicine (Baltimore). 2025 Jun 27;104(26):e43092. doi: 10.1097/MD.0000000000043092.
2
Developmental enamel defects and dental anomalies of number and size in children with growth hormone deficiency.生长激素缺乏症儿童的发育性牙釉质发育缺陷和牙齿数目及大小异常。
Sci Rep. 2023 Sep 7;13(1):14707. doi: 10.1038/s41598-023-41892-x.
3
Prostate biopsy free system for laparoscopic radical prostatectomy in a pituitary dwarfism: a case report.

本文引用的文献

1
Solitary Median Maxillary Central Incisor.孤立性上颌中切牙正中萌出
J Pediatr. 2015 Sep;167(3):770.e1. doi: 10.1016/j.jpeds.2015.06.010. Epub 2015 Jun 30.
2
[Influence on microstructure of dental zirconia ceramics prepared by two-step sintering].[两步烧结法制备牙科氧化锆陶瓷对其微观结构的影响]
Hua Xi Kou Qiang Yi Xue Za Zhi. 2013 Oct;31(5):496-9.
3
An Unusual Type II Dens Invaginatus with Calcified Canals in a Maxillary Lateral Incisor - A Case Report.上颌侧切牙伴钙化根管的罕见Ⅱ型牙内陷——病例报告
垂体性侏儒症患者腹腔镜根治性前列腺切除术中的前列腺活检游离系统:一例报告
Transl Androl Urol. 2020 Dec;9(6):2831-2835. doi: 10.21037/tau-20-489.
4
Variants in and are associated with small body size and a dental anomaly in dogs.在犬类中, 和 中的变异与小体型和牙齿异常有关。
Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24929-24935. doi: 10.1073/pnas.2009500117. Epub 2020 Sep 21.
J Clin Diagn Res. 2013 Sep;7(9):2084-5. doi: 10.7860/JCDR/2013/6325.3414. Epub 2013 Sep 10.
4
Endodontic retreatment of dens invaginatus presenting with gutta-percha overfilling at the attached gingiva and chronic apical periodontitis: unusual clinical report.附着龈处牙胶超充并伴有慢性根尖周炎的内陷牙根管再治疗:罕见临床报告
J Contemp Dent Pract. 2013 May 1;14(3):556-9. doi: 10.5005/jp-journals-10024-1362.
5
Diseases of the tooth: the genetic and molecular basis of inherited anomalies affecting the dentition.牙齿疾病:影响牙列的遗传性异常的遗传和分子基础。
Wiley Interdiscip Rev Dev Biol. 2013 Mar-Apr;2(2):183-212. doi: 10.1002/wdev.66. Epub 2012 May 25.
6
Solitary median maxillary central incisor, a clinical predictor of hypoplastic anterior pituitary, ectopic neurohypophysis and growth hormone deficiency.孤立性上颌中切牙正中萌出,是垂体前叶发育不全、异位神经垂体及生长激素缺乏的临床预测指标。
J Pediatr Endocrinol Metab. 2013;26(9-10):809-10. doi: 10.1515/jpem-2013-0128.
7
Assessing the quality of life of health-referred children and adolescents with short stature: development and psychometric testing of the QoLISSY instrument.评估因身材矮小而就诊的健康儿童和青少年的生活质量:QoLISSY 工具的开发和心理计量学测试。
Health Qual Life Outcomes. 2013 May 7;11:76. doi: 10.1186/1477-7525-11-76.
8
Different long-term response to growth hormone therapy in small- versus appropriate-for-gestational-age children with growth hormone deficiency.生长激素缺乏症的小于胎龄儿与适于胎龄儿对生长激素治疗的长期反应不同。
Horm Res Paediatr. 2013;79(4):214-9. doi: 10.1159/000350239. Epub 2013 Apr 26.
9
Growth hormone deficiency: an update.生长激素缺乏症:最新进展
Minerva Endocrinol. 2013 Mar;38(1):1-16.
10
Periodontal disease in adults with untreated congenital growth hormone deficiency: a case-control study.成人未治疗先天性生长激素缺乏症伴牙周病:病例对照研究。
J Clin Periodontol. 2011 Jun;38(6):525-31. doi: 10.1111/j.1600-051X.2011.01721.x. Epub 2011 Apr 13.