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内脏利什曼病相关噬血细胞综合征:一个来自非流行地区的两例意外诊断病例

Visceral leishmaniasis-associated hemophagocytosis: A tale of two unexpected diagnoses from a nonendemic region.

作者信息

Raina Rashmi Kaul, Raina Sujeet, Sharma Manupriya

机构信息

Department of Pathology, Dr. RPGMC, Kangra, Himachal Pradesh, India.

Department of Medicine, Dr. RPGMC, Kangra, Himachal Pradesh, India.

出版信息

Trop Parasitol. 2017 Jan-Jun;7(1):56-58. doi: 10.4103/2229-5070.202288.

Abstract

A case of visceral leishmaniasis (VL)-associated hemophagocytic lymphohistiocytosis (HLH) in an immunocompetent native from a nonendemic area was reported. The patient belonged to Ravi river valley area (altitude 996 meters above the mean sea level) of Chamba, Himachal Pradesh, India. VL and HLH were not a differential diagnosis. Identification of the Leishman-Donovan bodies and hemophagocytosis in bone marrow aspirate and biopsy provided the diagnosis. The patient recovered to the treatment with amphotericin B.

摘要

报告了一例来自非流行地区的免疫功能正常的本地人患内脏利什曼病(VL)相关噬血细胞性淋巴组织细胞增生症(HLH)的病例。该患者来自印度喜马偕尔邦恰姆巴的拉维河谷地区(海拔高于平均海平面996米)。VL和HLH并非鉴别诊断。骨髓穿刺和活检中利什曼-多诺万小体的鉴定及噬血细胞现象提供了诊断依据。患者接受两性霉素B治疗后康复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1934/5369278/0a98a9c430aa/TP-7-56-g002.jpg

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