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印度北阿坎德邦非流行山区的葡糖酸锑钠敏感型内脏利什曼病。

Sodium stibogluconate-sensitive visceral leishmaniasis in the non-endemic hilly region of Uttarakhand, India.

作者信息

Verma S K, Ahmad Sohaib, Shirazi Nadia, Kusum Anuradha, Kaushik R M, Barthwal S P

机构信息

Department of Medicine, Himalayan Institute of Medical Sciences, Swami Ram Nagar, Jolly Grant, P.O. Doiwala, Dehradun, Uttarakhand 248140, India.

出版信息

Trans R Soc Trop Med Hyg. 2007 Jul;101(7):730-2. doi: 10.1016/j.trstmh.2007.02.008. Epub 2007 Mar 23.


DOI:10.1016/j.trstmh.2007.02.008
PMID:17382981
Abstract

Although visceral leishmaniasis (VL) is endemic in various parts of India, mainly Bihar, West Bengal and Orissa, and neighbouring countries such as Nepal and Bangladesh, it is rarely reported from the hilly areas of India. We report on nine male VL cases from the non-endemic Garhwal region of Uttarakhand who were treated successfully with sodium stibogluconate. We conclude that sodium stibogluconate-sensitive VL is emerging in this region and that urgent and effective vector control measures may be warranted to prevent the disease from becoming a major health problem and to ensure that resistance to sodium stibogluconate does not emerge.

摘要

虽然内脏利什曼病(VL)在印度的各个地区(主要是比哈尔邦、西孟加拉邦和奥里萨邦)以及尼泊尔和孟加拉国等邻国呈地方性流行,但在印度山区却鲜有报道。我们报告了来自北阿坎德邦非流行区加瓦尔地区的9例男性VL病例,这些病例用葡萄糖酸锑钠治疗成功。我们得出结论,该地区正在出现对葡萄糖酸锑钠敏感的VL,可能需要采取紧急有效的病媒控制措施,以防止该病成为主要的健康问题,并确保不会出现对葡萄糖酸锑钠的耐药性。

相似文献

[1]
Sodium stibogluconate-sensitive visceral leishmaniasis in the non-endemic hilly region of Uttarakhand, India.

Trans R Soc Trop Med Hyg. 2007-7

[2]
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引用本文的文献

[1]
Rising visceral leishmaniasis in Holy Himalayas (Uttarakhand, India) - A cross-sectional hospital-based study.

J Family Med Prim Care. 2020-3-26

[2]
Visceral leishmaniasis-associated hemophagocytosis: A tale of two unexpected diagnoses from a nonendemic region.

Trop Parasitol. 2017

[3]
Role of Haematological Changes in Predicting Occurrence of Leishmaniasis- A Study in Kumaon Region of Uttarakhand.

J Clin Diagn Res. 2016-5

[4]
Case report: Expansion of visceral leishmaniasis to the western hilly part of Nepal.

Am J Trop Med Hyg. 2011-1

[5]
Climate change and threat of vector-borne diseases in India: are we prepared?

Parasitol Res. 2010-2-13

[6]
Evidence for involvement of TNFR1 and TIMPs in pathogenesis of post-kala-azar dermal leishmaniasis.

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