Koen Nastassja, Brittain Kirsty, Donald Kirsten A, Barnett Whitney, Koopowitz Sheri, Maré Karen, Zar Heather J, Stein Dan J
Department of Psychiatry and Mental Health, University of Cape Town.
Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town.
Psychol Trauma. 2017 May;9(3):292-300. doi: 10.1037/tra0000234.
To investigate the association between maternal posttraumatic stress disorder (PTSD) and infant development in a South African birth cohort.
Data from the Drakenstein Child Health Study were analyzed. Maternal psychopathology was assessed using self-report and clinician-administered interviews; and 6-month infant development using the Bayley III Scales of Infant Development. Linear regression analyses explored associations between predictor and outcome variables.
Data from 111 mothers and 112 infants (1 set of twins) were included. Most mothers (72%) reported lifetime trauma exposure; the lifetime prevalence of PTSD was 20%. Maternal PTSD was significantly associated with poorer fine motor and adaptive behavior - motor development; the latter remaining significant when adjusted for site, alcohol dependence, and infant head-circumference-for-age z score at birth.
Maternal PTSD may be associated with impaired infant neurodevelopment. Further work in low- and middle-income populations may improve early childhood development in this context. (PsycINFO Database Record
在南非一个出生队列中研究母亲创伤后应激障碍（PTSD）与婴儿发育之间的关联。
对德拉肯斯泰因儿童健康研究的数据进行分析。使用自我报告和临床医生访谈评估母亲的精神病理学状况；使用贝利婴幼儿发展量表第三版评估6个月大婴儿的发育情况。线性回归分析探讨预测变量和结果变量之间的关联。
纳入了111名母亲和112名婴儿（1对双胞胎）的数据。大多数母亲（72%）报告有终生创伤暴露经历；PTSD的终生患病率为20%。母亲的PTSD与较差的精细运动和适应性行为 - 运动发育显著相关；在对地点、酒精依赖和出生时婴儿头围与年龄的z评分进行调整后，后者仍然显著。
母亲的PTSD可能与婴儿神经发育受损有关。在低收入和中等收入人群中开展进一步研究可能会改善这一背景下的幼儿发育情况。（PsycINFO数据库记录
