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稳定期慢性阻塞性肺疾病中鼻高流量的应用:理论依据与生理学原理

Use of Nasal High Flow in Stable COPD: Rationale and Physiology.

作者信息

Pisani Lara, Vega Maria Laura

机构信息

a Department of Specialistic, Diagnostic and Experimental Medicine (DIMES), Respiratory and Critical Care, Sant'Orsola Malpighi Hospital, Alma Mater Studiorum , University of Bologna , Bologna , Italy.

b Department of Physical Therapy, Fundacion Favaloro University Hospital , UCI , Buenos Aires , Argentina.

出版信息

COPD. 2017 Jun;14(3):346-350. doi: 10.1080/15412555.2017.1315715. Epub 2017 May 1.

DOI:10.1080/15412555.2017.1315715
PMID:28459282
Abstract

High-flow nasal cannula (HFNC) is a device able to deliver heated and humidified oxygen at high flows (up to 60 L/minutes). Potential benefits of HFNC are several and include the improvement of lung mucociliary clearance, the washout of upper airway dead space, the generation of a low level of positive airway pressure (PEEP effect), the decrease in inspiratory resistance and at the same time the increase in expiratory resistance. The present review aimed to describe the evidence surrounding the use of HFNC in stable chronic obstructive pulmonary disease patients.

摘要

高流量鼻导管(HFNC)是一种能够以高流量(高达60升/分钟)输送加热和加湿氧气的设备。HFNC有诸多潜在益处,包括改善肺部黏液纤毛清除功能、清除上呼吸道死腔、产生低水平的气道正压(呼气末正压效应)、降低吸气阻力以及同时增加呼气阻力。本综述旨在描述关于HFNC在稳定期慢性阻塞性肺疾病患者中应用的相关证据。

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