慢性呼吸道疾病患者的家庭高流量治疗：生理原理与临床结果
Home High-Flow Therapy in Patients with Chronic Respiratory Diseases: Physiological Rationale and Clinical Results.
作者信息
Vega Pittao Maria Laura, Schifino Gioacchino, Pisani Lara, Nava Stefano
机构信息
Alma Mater Studiorum, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.
Respiratory and Critical Care Unit, IRCCS Azienda Ospedaliero Universitaria di Bologna, 40138 Bologna, Italy.
出版信息
J Clin Med. 2023 Apr 3;12(7):2663. doi: 10.3390/jcm12072663.
High-flow therapy (HFT) is the administration of gas flows above 15 L/min. It is a non-invasive respiratory support that delivers heated (up to 38 °C), humidified (100% Relative Humidity, RH; 44 mg HO/L Absolute Humidity, AH), oxygen-enriched air when necessary, through a nasal cannula or a tracheostomy interface. Over the last few years, the use of HFT in critically ill hypoxemic adults has increased. Although the clinical benefit of home high-flow therapy (HHFT) remains unclear, some research findings would support the use of HHFT in chronic respiratory diseases. The aim of this review is to describe the HFT physiological principles and summarize the published clinical findings. Finally, we will discuss the differences between hospital and home implementation, as well as the various devices available for HHFT application.
高流量疗法（HFT）是指输送流量高于15升/分钟的气体。它是一种无创呼吸支持方式，必要时通过鼻导管或气管造口接口输送加热至38°C、加湿（相对湿度100%；绝对湿度44毫克水/升）、富氧的空气。在过去几年中，高流量疗法在危重症低氧血症成人患者中的应用有所增加。尽管家庭高流量疗法（HHFT）的临床益处尚不清楚，但一些研究结果支持在慢性呼吸系统疾病中使用HHFT。本综述的目的是描述高流量疗法的生理原理，并总结已发表的临床研究结果。最后，我们将讨论医院和家庭实施高流量疗法的差异，以及可用于家庭高流量疗法的各种设备。
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