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多接入活体生物遥测技术:超声弹性成像和 M 型超声成像的应用

Multiaccess In Vivo Biotelemetry Using Sonomicrometry and M-Scan Ultrasound Imaging.

出版信息

IEEE Trans Biomed Eng. 2018 Jan;65(1):149-158. doi: 10.1109/TBME.2017.2697998. Epub 2017 Apr 25.

DOI:10.1109/TBME.2017.2697998
PMID:28459681
Abstract

UNLABELLED

Objective: In this paper, we investigate the use of commercial off-the-shelf diagnostic ultrasound readers to achieve multiaccess wireless in vivo telemetry with millimeter-sized sonomicrometry crystal transducers.

METHODS

The sonomicrometry crystals generate ultrasonic pulses that supersede the echoes generated at the tissue interfaces in response to M-scan interrogation pulses. The traces of these synthetic pulses are captured on an M-scan image and the transmitted data are decoded using image deconvolution and deblurring algorithms.

RESULTS

Using a chicken phantom and 1.3 MHz sonomicrometry crystals of diameter 1 mm, we first demonstrate that a standard ultrasound reader can achieve biotelemetry data rates up to 1 Mb/s for implantation depths greater than 10 cm. For this experiment the maximum power dissipation at the crystals was measured to be 20 and bit-error-rate of the telemetry link was shown to be . We also demonstrate the use of this method for multiaccess biotelemetry where several sonomicrometry crystals simultaneously transmit the data using different modulation and coding techniques. Using a live ovine model, we demonstrate a sonomicrometry crystal implanted in the sheep 's tricuspid valve can maintain a continuous, reliable telemetry link at data rates up tob 800 Kb/s in the presence of respiratory and cardiac motion artifacts.

CONCLUSION

Compared to existing radio-frequency and ultrasound based biotelemetry devices, the reported data-rates are significantly higher considering the transducer's form-factor and its implantation depth.

SIGNIFICANCE

The proposed technique thus validates the feasibility of establishing reliable communication link with multiple in vivo implants using M-scan-based ultrasound imaging.

摘要

未加标签

目的:在本文中,我们研究了使用商用现成的诊断超声读取器来实现具有毫米级声纳微测晶体换能器的多接入无线体内遥测。

方法

声纳微测晶体产生超声脉冲,这些脉冲会取代组织界面处响应 M 扫描询问脉冲产生的回波。这些合成脉冲的迹线被捕获在 M 扫描图像上,并使用图像反卷积和去模糊算法对传输数据进行解码。

结果

使用鸡模型和 1.3 MHz 直径为 1 毫米的声纳微测晶体,我们首先证明标准超声读取器可以实现植入深度大于 10 厘米时高达 1 Mb/s 的生物遥测数据速率。对于该实验,测量到晶体的最大功耗为 20 ,并且遥测链路的误码率表明为. 我们还展示了该方法在多接入生物遥测中的应用,其中几个声纳微测晶体同时使用不同的调制和编码技术传输数据。使用活体绵羊模型,我们证明了在存在呼吸和心脏运动伪影的情况下,植入绵羊三尖瓣的声纳微测晶体可以以高达 800 Kb/s 的数据速率保持连续可靠的遥测链路。

结论

与现有的射频和超声生物遥测设备相比,考虑到换能器的形状因数及其植入深度,报告的数据速率要高得多。

意义

因此,所提出的技术验证了使用基于 M 扫描的超声成像技术与多个体内植入物建立可靠通信链路的可行性。

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