i(12p)阴性睾丸生殖细胞肿瘤。是一个不同的类别吗？
i(12p)-negative testicular germ cell tumors. A different group?
作者信息
Castedo S M, de Jong B, Oosterhuis J W, Seruca R, Idenburg V J, Buist J, Sleijfer D T
机构信息
Department of Human Genetics, State University of Groningen, The Netherlands.
出版信息
Cancer Genet Cytogenet. 1988 Oct 15;35(2):171-8. doi: 10.1016/0165-4608(88)90239-7.
PMID:2846146
Abstract
Cytogenetic analysis was performed of three seminomas, two primary nonseminomas, and two mature residual teratomas following chemotherapy, all lacking i(12p). Testicular germ cell tumors without an i(12p) may represent a subgroup of germ cell tumors, also in their clinical course, compared with those having i(12p).
摘要
对3例精原细胞瘤、2例原发性非精原细胞瘤以及2例化疗后的成熟残余畸胎瘤进行了细胞遗传学分析，所有病例均缺乏12号染色体短臂等臂染色体（i(12p)）。与具有i(12p)的睾丸生殖细胞肿瘤相比，没有i(12p)的睾丸生殖细胞肿瘤可能代表生殖细胞肿瘤的一个亚组，在其临床病程方面也是如此。
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