Familial double testicular tumors: identical chromosome changes in seminoma and embryonal carcinoma of the same testis.
作者信息
Haddad F S, Sorini P M, Somsin A A, Nathan M H, Dobbs R M, Berger C S, Sandberg A A
机构信息
Veterans Administration Hospital, Phoenix, Arizona.
出版信息
J Urol. 1988 Apr;139(4):748-50. doi: 10.1016/s0022-5347(17)42621-8.
PMID:3352038
Abstract
An identical abnormal chromosome, i(12p), and a marker chromosome of unknown origin were seen in 2 tumors of different histology (seminoma and embryonal carcinoma) in the same testis. A younger brother of the patient also had undergone orchiectomy for 2 seminomas in the left testis 2 years previously. These findings are discussed in relation to the possible cellular background of testicular tumors and their genetic parameters.
摘要
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