Bomanji J, Conry B G, Britton K E, Reznek R H
Department of Nuclear Medicine, St Bartholomew's Hospital, London.
Clin Radiol. 1988 Sep;39(5):502-6. doi: 10.1016/s0009-9260(88)80214-9.
Iodine-123 metaiodobenzylguanidine (MIBG) has been used as a diagnostic agent for imaging neural crest tumours. In a retrospective study of 27 patients, the role of 123I MIBG scintigraphy and X-ray computed tomography (CT) for detection of disease was compared. Both imaging techniques were accurate in the identification of these tumours. Iodine-123 MIBG was slightly more accurate in detecting metastatic disease. Computed tomography of tumours was useful in planning appropriate metastatic intervention. We suggest 123I MIBG should be the primary imaging procedure followed by CT in the investigation of these patients.
碘-123间碘苄胍(MIBG)已被用作神经嵴肿瘤成像的诊断剂。在一项对27例患者的回顾性研究中,比较了123I MIBG闪烁扫描术和X线计算机断层扫描(CT)在疾病检测中的作用。两种成像技术在识别这些肿瘤方面都很准确。碘-123 MIBG在检测转移性疾病方面略更准确。肿瘤的计算机断层扫描有助于规划适当的转移性干预措施。我们建议在对这些患者进行检查时,应以123I MIBG作为主要成像程序,随后进行CT检查。