The human amiloride-sensitive Na+/H+ antiporter: localization to chromosome 1 by in situ hybridization.
作者信息
Mattei M G, Sardet C, Franchi A, Pouysségur J
机构信息
INSERM U242, Centre de Génétique Médicale, Hôpital d'enfants de la Timone, Marseille, France.
出版信息
Cytogenet Cell Genet. 1988;48(1):6-8. doi: 10.1159/000132575.
PMID:2846238
Abstract
The Na+/H+ antiporter is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. We cloned the human gene capable of complementing antiporter-deficient mouse fibroblasts and isolated an exon-containing genomic DNA fragment. Using this genomic probe, we mapped the putative structural gene of the amiloride-sensitive Na+/H+ antiporter to the human chromosome region 1p35----p36.1 by in situ hybridization.
摘要
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