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[胃癌患者行胃切除联合脾切除术后血液淋巴细胞的抑制功能]

[Suppressor function of the blood lymphocytes in patients with stomach cancer undergoing gastrectomy combined with splenectomy].

作者信息

Kadagidze Z G, Zhogoleva I B, Popova S R, Ibragimov S S

出版信息

Eksp Onkol. 1988;10(4):46-9.

PMID:2846261
Abstract

Suppressor status of immunity in 34 patients with gastric cancer of the III-IV stages was studied before and after (15 days and 3 months) gastrectomy and gastrosplenectomy. The control group consisted of 42 healthy donors. It was shown that gastrectomy caused inhibition of the endogenous activity, but stimulated the function of the prostaglandin-producing suppressor cells while combined gastrosplenectomy induced inhibition of the function of both endogenous and prostaglandin-producing suppressor cells.

摘要

对34例Ⅲ - Ⅳ期胃癌患者在胃切除术和胃脾切除术前后(15天和3个月)的免疫抑制状态进行了研究。对照组由42名健康供者组成。结果表明,胃切除术导致内源性活性受到抑制,但刺激了产生前列腺素的抑制细胞的功能,而联合胃脾切除术则对内源性和产生前列腺素的抑制细胞的功能均产生抑制作用。

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