Saito H, Kikkawa H, Bando H, Sakatoku M, Hirano M, Tatsuzawa T
Dept. of Surgery, Koseiren Takaoka Hospital.
Gan No Rinsho. 1988 Nov;34(14):1965-8.
A SU-polysaccharide skin test (SU-PS test) has been employed and studied as a parameter for monitoring the immunological status of OK-432 treated patients who had undergone a curative gastrectomy for a gastric cancer in stages II and III. The median diameter of the erythema (SU-PS value) was found to have no relation to the number of lymphocytes and the serum protein level and was depressed by combined chemotherapy. The SU-PS value was significantly higher in patients not given a splenectomy than in patients who had undergone a patients splenectomy. The spleen is considered the essential organ to focus on in OK-432 immunotherapy.
已采用并研究了一种链球菌制剂-多糖皮肤试验（SU-PS试验），作为监测接受OK-432治疗且已接受II期和III期胃癌根治性胃切除术患者免疫状态的一个参数。发现红斑的中位直径（SU-PS值）与淋巴细胞数量和血清蛋白水平无关，且联合化疗会使其降低。未行脾切除术的患者的SU-PS值显著高于行脾切除术的患者。脾脏被认为是OK-432免疫治疗中需要重点关注的重要器官。
