Yao Kouamé Hubert, Tanon Aristophane Koffi, Lagou Adjoua Delphine, Konan Serge Didier, Diopoh Séry Patrick, Meite Fatou
Service de néphrologie-médecine interne, CHU Treichville, BP V3 Abidjan 01, Abidjan, Cote d'Ivoire.
Service des maladies infectieuses et tropicales, CHU Treichville, BP V3 Abidjan 01, Abidjan, Cote d'Ivoire.
Nephrol Ther. 2017 May;13(3):168-175. doi: 10.1016/j.nephro.2016.10.003. Epub 2017 Apr 24.
Acute kidney injury (AKI) is commonly associated with HIV infection.
To describe the profile of AKI in HIV infected versus non-infected persons.
This is a prospective study that was carried out during the study period from January 2010 to December 2015 in the department of nephrology-internal medicine D of Treichville University Hospital (Côte d'Ivoire).
The prevalence of HIV infection was 35.2% in the population of AKI. The average age of patients was 42±18 years in the HIV positive group against 51±18 years in the HIV negative group (P=0.0001). Etiologies were infections in 65.1% in the HIV positive group against 38.8% in the HIV negative group (P=0.0001) and water loss in 24.7% in the HIV positive group against 7.8% in the HIV negative group (P=0.0001). Factors such as the AIDS stage (P=0.002), severe sepsis (P=0.002) and acute pyelonephritis (P=0.001) were associated with mortality in HIV positive patients against severe anemia (P=0.0001) and severe sepsis (P=0.0001) in the HIV-negative group.
HIV positive patients are younger with a female predominance. The mortality rate is identical in both groups.
急性肾损伤（AKI）通常与HIV感染相关。
描述HIV感染者与未感染者中急性肾损伤的情况。
这是一项前瞻性研究，于2010年1月至2015年12月在特雷什维尔大学医院（科特迪瓦）内科肾病科D进行。
急性肾损伤患者人群中HIV感染率为35.2%。HIV阳性组患者平均年龄为42±18岁，而HIV阴性组为51±18岁（P = 0.0001）。HIV阳性组病因中感染占65.1%，HIV阴性组为38.8%（P = 0.0001）；HIV阳性组水分丢失占24.7%，HIV阴性组为7.8%（P = 0.0001）。艾滋病阶段（P = 0.002）、严重脓毒症（P = 0.002）和急性肾盂肾炎（P = 0.001）等因素与HIV阳性患者死亡率相关，而严重贫血（P = 0.0001）和严重脓毒症（P = 0.0001）与HIV阴性组死亡率相关。
HIV阳性患者更年轻，以女性为主。两组死亡率相同。
