Hanna Cameron C, Kulkarni Sameer S, Watson Emma E, Premdjee Bhavesh, Payne Richard J
School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia.
Chem Commun (Camb). 2017 May 11;53(39):5424-5427. doi: 10.1039/c7cc00823f.
Peptide selenoesters have recently emerged as key building blocks for the ligation-based assembly of large polypeptides and proteins. Herein, we report an efficient solid-phase method for the high yielding and epimerisation-free synthesis of peptide selenoesters using a side-chain immobilisation strategy.
肽硒酯最近已成为基于连接的大型多肽和蛋白质组装的关键构件。在此，我们报道了一种使用侧链固定策略高效固相合成肽硒酯的方法，该方法产率高且无差向异构化。
