Zhu Ziqiang, Shang Xiaoping, Qi Peiyi, Ma Shengli
Department of Emergency, The First Affiliated Hospital of Zhengzhou University, No.1 Jian She Dong Avenue, Zhengzhou, 450002, People's Republic of China.
Department of Medical Records, The First Affiliated Hospital of Zhengzhou University, No.1 Jian She Dong Avenue, Zhengzhou, 450002, People's Republic of China.
Scand J Trauma Resusc Emerg Med. 2017 May 2;25(1):47. doi: 10.1186/s13049-017-0389-6.
Experimental research suggests that females have a higher survival rate after trauma, although this claim is controversial. This study sought to determine the role of sex on mortality among trauma patients in China.
The study enrolled 1789 trauma patients who visited the Emergency Intensive Care Unit of the First Affiliated Hospital of Zhengzhou University during 2015 and 2016. A retrospective data analysis was performed to determine sex-based differences after blunt trauma. Patients were stratified by age and injury severity (using the Injury Severity Score). Multiple logistic regression was used to analyze the association between sex and post-injury complications and mortality.
Female trauma patients experienced a significantly lower risk of mortality than males (odds ratio, 0.931; 95% confidence interval, 0.883-0.982). This survival advantage of females was particularly notable in the 'younger than 45 years' age group. Sex-based differences were also found in the occurrence of life-threatening complications after trauma.
This study demonstrated that females are more likely to survival after severe blunt trauma and also have less inpatient complications than men, suggesting an important role for sex hormones after severe traumatic injury.
实验研究表明，女性创伤后生存率较高，尽管这一说法存在争议。本研究旨在确定性别在中国创伤患者死亡率中的作用。
该研究纳入了2015年至2016年期间就诊于郑州大学第一附属医院急诊重症监护病房的1789例创伤患者。进行回顾性数据分析以确定钝性创伤后的性别差异。患者按年龄和损伤严重程度（使用损伤严重度评分）进行分层。采用多因素逻辑回归分析性别与伤后并发症及死亡率之间的关联。
女性创伤患者的死亡风险显著低于男性（比值比，0.931；95%置信区间，0.883-0.982）。女性的这种生存优势在“45岁以下”年龄组尤为明显。创伤后危及生命并发症的发生也存在性别差异。
本研究表明，女性在严重钝性创伤后更易存活，且住院并发症也少于男性，提示性激素在严重创伤性损伤后起重要作用。
