Cohen P R
University of Texas Medical School at Houston, USA.
Am Fam Physician. 1995 Apr;51(5):1199-204.
A new or unusual skin lesion may be the first sign of an internal malignancy, a primary skin cancer or a cutaneous metastasis of carcinoma in another site. Patients with carcinoma that has metastasized to the skin commonly present with lesions in the area overlying the neoplasm, but the morphology, pattern and distribution of cutaneous metastases may vary. Patients with sarcoma, leukemia or lymphoma may also initially present with cutaneous lesions, or lesions may develop later in the course of the disease. Biopsies of suspicious lesions should always be performed.
一种新的或不寻常的皮肤病变可能是内部恶性肿瘤、原发性皮肤癌或其他部位癌的皮肤转移的首发迹象。癌已转移至皮肤的患者通常在肿瘤上方区域出现病变，但皮肤转移的形态、模式和分布可能有所不同。肉瘤、白血病或淋巴瘤患者也可能最初表现为皮肤病变，或者病变可能在疾病过程中稍后出现。对于可疑病变应始终进行活检。
