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电超敏反应(EHS)患者唾液α淀粉酶水平升高。

Increasing levels of saliva alpha amylase in electrohypersensitive (EHS) patients.

作者信息

Andrianome Soafara, Hugueville Laurent, de Seze René, Selmaoui Brahim

机构信息

a Department of Experimental Toxicology , Institut National de l'Environnement Industriel et des Risques (INERIS) , Verneuil-en-Halatte , France.

b Peritox-Laboratoire de Périnatalité et Risques Toxiques UMR-I-01 Unité mixte INERIS , Université de Picardie Jules Verne , Amiens , France.

出版信息

Int J Radiat Biol. 2017 Aug;93(8):841-848. doi: 10.1080/09553002.2017.1325971. Epub 2017 May 17.

DOI:10.1080/09553002.2017.1325971
PMID:28466664
Abstract

PURPOSE

To assess the level of various salivary and urinary markers of patients with electromagnetic hypersensitivity (EHS) and to compare them with those of a healthy control group.

MATERIALS AND METHODS

We analyzed samples from 30 EHS individuals and a matched control group of 25 individuals (non-EHS) aged between 22 and 66. We quantified cortisol both in saliva and urine, alpha amylase (sAA), immunoglobulin A and C Reactive Protein levels in saliva and neopterin in urine (uNeopterin).

RESULTS

sAA was found to be significantly higher (p < 0.005) in the EHS group. uNeopterin and sAA analysis showed a significant difference based on the duration of EHS.

CONCLUSION

Higher levels of sAA in EHS participants may suggest that the sympathetic adrenal medullar system is activated. However, most of the analyzed markers of the immune system, sympathetic activity and circadian rhythm did not vary significantly in the EHS group. There is a trend to the higher levels of some variables in subgroups according to the EHS duration.

摘要

目的

评估电磁超敏反应(EHS)患者的各种唾液和尿液标志物水平,并将其与健康对照组进行比较。

材料与方法

我们分析了30名EHS个体以及25名年龄在22至66岁之间的匹配对照组个体(非EHS)的样本。我们对唾液和尿液中的皮质醇、唾液中的α淀粉酶(sAA)、免疫球蛋白A和C反应蛋白水平以及尿液中的新蝶呤(uNeopterin)进行了定量分析。

结果

发现EHS组中的sAA显著更高(p < 0.005)。uNeopterin和sAA分析显示,根据EHS的持续时间存在显著差异。

结论

EHS参与者中较高水平的sAA可能表明交感肾上腺髓质系统被激活。然而,EHS组中大多数分析的免疫系统、交感神经活动和昼夜节律标志物没有显著变化。根据EHS持续时间,亚组中某些变量有升高的趋势。

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