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莫桑比克流动矿工及其女性伴侣使用短期口服暴露前预防(PrEP)的意愿。

Willingness to use short-term oral pre-exposure prophylaxis (PrEP) by migrant miners and female partners of migrant miners in Mozambique.

作者信息

Falcao Joana, Ahoua Laurence, Zerbe Allison, di Mattei Pietro, Baggaley Rachel, Chivurre Victor, Mulondo Prince, Ramiro Isaias, Dalal Shona, Morales Fernando, O'Reilly Kevin, El-Sadr Wafaa

机构信息

a ICAP, Mailman School of Public Health , Columbia University , Maputo , Mozambique.

b ICAP, Mailman School of Public Health, ICAP , Columbia University , New York , USA.

出版信息

Cult Health Sex. 2017 Dec;19(12):1389-1403. doi: 10.1080/13691058.2017.1316424. Epub 2017 May 4.

DOI:10.1080/13691058.2017.1316424
PMID:28468533
Abstract

Migrant miners from Mozambique who work in South Africa and their partners are at substantial risk for HIV infection. We conducted a cross-sectional study to assess the willingness of migrant miners and female partners of miners to take short-term pre-exposure prophylaxis (PrEP) for prevention of HIV acquisition. The study was conducted in Gaza Province, Mozambique, between September and October 2015. A total of 131 male miners and female partners of male miners completed a questionnaire. Subsequently, 48 in-depth interviews among male miners and female partners of miners and 3 focus-group discussions (6 participants each) among female partners of miners were conducted. Quantitative data were tabulated using Stata. A structured coding scheme was developed and qualitative data were analysed using Atlas.ti. Most participants (94%) were willing to take PrEP for short-term use. Facilitating factors for willingness to use PrEP were concerns about partner's sexual behaviour, desire for pregnancy and one's own sexual behaviour. The main barriers to PrEP use were concerns regarding side-effects, perceived difficulty adhering to daily pill taking and concern about partner/family disapproval. Overall, participants saw potential barriers for PrEP as minor obstacles that could be overcome. The male partner's influence on PrEP use was significant.

摘要

在南非工作的莫桑比克流动矿工及其伴侣面临着很高的艾滋病毒感染风险。我们开展了一项横断面研究,以评估流动矿工及其女性伴侣接受短期暴露前预防(PrEP)以预防艾滋病毒感染的意愿。该研究于2015年9月至10月在莫桑比克加沙省进行。共有131名男性矿工及其女性伴侣完成了一份调查问卷。随后,对男性矿工及其女性伴侣进行了48次深入访谈,并对矿工女性伴侣进行了3次焦点小组讨论(每次6名参与者)。定量数据使用Stata制表。制定了结构化编码方案,并使用Atlas.ti分析定性数据。大多数参与者(94%)愿意短期使用PrEP。愿意使用PrEP的促进因素包括对伴侣性行为的担忧、对怀孕的渴望以及自身的性行为。使用PrEP的主要障碍是对副作用的担忧、认为坚持每日服药困难以及担心伴侣/家人反对。总体而言,参与者认为PrEP的潜在障碍是可以克服的小障碍。男性伴侣对PrEP使用的影响很大。

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