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与正在服用艾滋病毒暴露前预防药物(PrEP)的男性发生性行为并使用该药物的意愿:2011 - 2015年澳大利亚男同性恋者和双性恋男性在线调查结果

Willingness to use and have sex with men taking HIV pre-exposure prophylaxis (PrEP): results of online surveys of Australian gay and bisexual men, 2011-2015.

作者信息

Holt Martin, Lea Toby, Schmidt Heather-Marie, Kolstee Johann, Ellard Jeanne, Murphy Dean, Truong Hong-Ha, de Wit John

机构信息

Centre for Social Research in Health, UNSW Australia, Sydney, New South Wales, Australia.

Centre for Population Health, New South Wales Ministry of Health, Sydney, New South Wales, Australia.

出版信息

Sex Transm Infect. 2017 Sep;93(6):438-444. doi: 10.1136/sextrans-2016-052774. Epub 2017 Jan 20.

Abstract

OBJECTIVE

Assess willingness to use HIV pre-exposure prophylaxis (PrEP), support for others using it and willingness to have sex with partners using PrEP among Australian gay and bisexual men (GBM).

METHODS

National, online cross-sectional surveys of Australian GBM were conducted in 2011, 2013 and 2015. Scales measuring support for and willingness to have sex with men using PrEP were developed in 2015 using factor analysis. Trends and associations with key measures were analysed using multivariate logistic regression.

RESULTS

During 2011-2015, 3850 surveys were completed by GBM. Willingness to use PrEP among HIV-negative and untested men did not change between 2011 (28.2%) and 2015 (31.7%, p=0.13). In 2015, willingness to use PrEP was independently associated with younger age, having an HIV-positive regular partner, recent condomless anal intercourse with casual male partners (CAIC), more than 10 male sex partners in the previous 6 months, ever having taken postexposure prophylaxis and having fewer concerns about using PrEP. In 2015, 54.5% of GBM supported other GBM taking PrEP and 39% were willing to have sex with men using PrEP. Support for and willingness to have sex with PrEP users were both associated with being HIV-positive, having a university degree and having two or more male partners in the previous 6 months. Willingness to have sex with men on PrEP was also associated with recent CAIC and using party drugs for sex, but was less likely among men who consistently used or had a positive experience using condoms.

DISCUSSION

Interest in and support for using PrEP are concentrated among men who engage in higher risk practices and who know more about living with HIV. This is consistent with the targeting of PrEP in Australia.

摘要

目的

评估澳大利亚男同性恋者和双性恋男性(GBM)使用HIV暴露前预防(PrEP)的意愿、对他人使用PrEP的支持度以及与使用PrEP的伴侣发生性行为的意愿。

方法

在2011年、2013年和2015年对澳大利亚GBM进行了全国性在线横断面调查。2015年采用因子分析制定了衡量对使用PrEP的男性的支持度以及与其发生性行为意愿的量表。使用多变量逻辑回归分析趋势及与关键指标的关联。

结果

在2011 - 2015年期间,GBM完成了3850份调查问卷。HIV阴性且未检测的男性中使用PrEP的意愿在2011年(28.2%)和2015年(31.7%,p = 0.13)之间没有变化。2015年,使用PrEP的意愿与年龄较小、有HIV阳性的固定伴侣、近期与男性性伴侣有无保护肛交(CAIC)、在过去6个月内有超过10名男性性伴侣、曾接受暴露后预防以及对使用PrEP的担忧较少独立相关。2015年,54.5%的GBM支持其他GBM使用PrEP,39%愿意与使用PrEP的男性发生性行为。对PrEP使用者的支持度以及与其发生性行为的意愿均与HIV呈阳性、拥有大学学位以及在过去6个月内有两个或更多男性伴侣相关。与使用PrEP的男性发生性行为的意愿还与近期CAIC以及使用派对药物进行性行为有关,但在持续使用避孕套或使用避孕套有积极体验的男性中可能性较小。

讨论

对使用PrEP的兴趣和支持集中在从事更高风险行为且对HIV感染生活了解更多的男性中。这与澳大利亚PrEP的目标人群一致。

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