Maruyama C, Yamamichi N, Serikawa F, Ishii E, Matsunou H, Konishi F, Kikuchi M, Tsunamura Y
Dept. of Pathology, Kanazawa Medical Univ.
Gan No Rinsho. 1988 Sep;34(11):1603-6.
A rare case of a primary signet-ring cell carcinoma of the sigmoid colon in a 66-year-old man is reported. Endoscopically, a sessile polyp, 2 cm in diameter, was found in sigmoid colon, consisting mainly of a well differentiated adenocarcinoma and, partially of a signet-ring cell carcinoma. A residual polyp was found at the same site in the sigmoid colon, sixth months after surgery. The resected polyp was histologically confirmed as being a signet-ring cell carcinoma, which had infiltrated into submucosal space by scirrhous invasion. After a polypectomy, a partial colectomy was performed and no carcinoma cells have been identified in the resected colon. We have speculated that this signet-ring cell polyp could develop into Borrmann type 4 advanced colon cancer.
报告了一例66岁男性乙状结肠原发性印戒细胞癌的罕见病例。内镜检查发现乙状结肠有一个直径2厘米的无蒂息肉,主要由高分化腺癌组成,部分为印戒细胞癌。术后6个月,在乙状结肠同一部位发现残留息肉。切除的息肉经组织学证实为印戒细胞癌,已通过硬癌浸润侵入黏膜下层。息肉切除术后,进行了部分结肠切除术,切除的结肠中未发现癌细胞。我们推测这种印戒细胞息肉可能发展为Borrmann 4型晚期结肠癌。