Kiiskinen Salla J, Ojanen Tarja, Björkman Yvonne, Laitinen Harri, Siitonen Anja
Bacterial Infections Unit, Department of Infectious Diseases, National Institute for Health and Welfare (THL), Helsinki, Finland.
Labquality Ltd, Helsinki, Finland.
Microbiol Insights. 2017 Feb 16;10:1178636117691253. doi: 10.1177/1178636117691253. eCollection 2017.
In Finland, all laboratories carrying out diagnostics of infectious diseases in humans are approved by the Regional State Administrative Agencies and are obligated to participate in External Quality Assurance rounds. Performance in these rounds is thought to reflect the quality of laboratory work. In the 6-year study period, 17 Finnish laboratories received 48 simulated faecal specimens for the culturing of diarrhoeal pathogens, yielding altogether 586 faecal culture External Quality Control specimens and 581 reports. The results were correct in 92% of all reports and in 67% of all specimens. False-negative results were given for 2 of the 18 specimens, one with biochemically atypical strain and the other with a low count of cells. False-negative report was given for 6 of the 7 specimens in some participating laboratory. Detection of all common faecal pathogens is especially relevant to patient safety, public health, and epidemiological surveillance.
在芬兰，所有从事人类传染病诊断的实验室均需经地区国家行政机构批准，并必须参加外部质量保证轮次。这些轮次的表现被认为反映了实验室工作的质量。在为期6年的研究期间，17家芬兰实验室收到了48份模拟粪便标本用于培养腹泻病原体，共产生了586份粪便培养外部质量控制标本和581份报告。所有报告中有92%的结果正确，所有标本中有67%的结果正确。18份标本中有2份给出了假阴性结果，其中一份是生化非典型菌株，另一份是细胞计数低。在某个参与实验室的7份标本中有6份给出了假阴性报告。检测所有常见的粪便病原体对患者安全、公共卫生和流行病学监测尤为重要。
