Wali Siraj Omar, Abalkhail Bahaa, Krayem Ayman
Sleep Medicine and Research Center, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
Department of Family and Community Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Ann Thorac Med. 2017 Apr-Jun;12(2):88-94. doi: 10.4103/1817-1737.203746.
Obstructive sleep apnea (OSA) is a common disorder worldwide; however, epidemiological studies on its prevalence lack in Saudi Arabia. This study aimed to determine the prevalence and risk factors of OSA in Saudi Arabia.
The study was performed from 2013 to 2015 in two stages. The screening stage was first; a random sample of Saudi employees ( = 2682) 30-60 years of age completed a survey that included the Wisconsin questionnaire. According to these data, the subjects were categorized as habitual, moderate, or nonsnorers (NSs). The confirmatory second stage was a case-control study conducted on 346 individuals selected from each group using polysomnography (PSG).
In the first stage, the prevalence of habitual snoring was 23.5%, moderate snoring was16.6%, while 59.9% of the sample was NSs. Among the 346 individuals who underwent PSG, a total of 235 (67.9%) subjects had OSA with an apnea-hypopnea index (AHI) of ≥5; 76 (22.0%) had OSA syndrome (OSAS), defined by an AHI of ≥5 plus daytime sleepiness; and 227 (65.6%) had clinically diagnosed OSA syndrome (COSAS), as defined by the American Academy of Sleep Medicine. A conservative estimate of at least 8.8% (12.8% in men and 5.1% in women) was calculated for the overall prevalence of OSA. Similarly, the overall estimated prevalence of OSAS and COSAS was 2.8% (4.0% in men and 1.8% in women) and 8.5% (12.4% in men and 4.8% in women), respectively. A multivariate analysis revealed age, gender, obesity, and hypertension as independent risk factors of OSA.
Our study demonstrated that the rate and risk factors of OSA in the Saudi population are similar to those observed in Western studies.
阻塞性睡眠呼吸暂停(OSA)是一种全球范围内常见的疾病;然而,沙特阿拉伯缺乏关于其患病率的流行病学研究。本研究旨在确定沙特阿拉伯OSA的患病率及危险因素。
该研究于2013年至2015年分两个阶段进行。首先是筛查阶段;随机抽取2682名年龄在30至60岁的沙特员工完成一项包含威斯康星问卷的调查。根据这些数据,将受试者分为习惯性打鼾者、中度打鼾者或非打鼾者(NSs)。验证性的第二阶段是一项病例对照研究,对从每组中选取的346名个体进行多导睡眠图(PSG)检查。
在第一阶段,习惯性打鼾的患病率为23.5%,中度打鼾为16.6%,而59.9%的样本为非打鼾者。在接受PSG检查的346名个体中,共有235名(67.9%)受试者患有OSA,呼吸暂停低通气指数(AHI)≥5;76名(22.0%)患有阻塞性睡眠呼吸暂停综合征(OSAS),定义为AHI≥5加日间嗜睡;227名(65.6%)患有临床诊断的阻塞性睡眠呼吸暂停综合征(COSAS),这是根据美国睡眠医学学会的定义。OSA总体患病率的保守估计至少为8.8%(男性为12.8%,女性为5.1%)。同样,OSAS和COSAS的总体估计患病率分别为2.8%(男性为4.0%,女性为1.8%)和8.5%(男性为12.4%,女性为4.8%)。多因素分析显示年龄、性别、肥胖和高血压是OSA的独立危险因素。
我们的研究表明,沙特人群中OSA的发生率和危险因素与西方研究中观察到的相似。