扩散加权成像的表观扩散系数在原发性实性和囊性肾肿块鉴别诊断中的应用价值
Usefulness of Apparent Diffusion Coefficient of Diffusion-Weighted Imaging for Differential Diagnosis of Primary Solid and Cystic Renal Masses.
作者信息
Öztürk Mehmet, Ekinci Afra, Elbir Şenol Fatih, Okur Aylin, Doğan Serap, Karahan Ökkeş Ibrahim
机构信息
Department of Radiology, Diyarbakır Children's Hospital, Diyarbakır, Turkey.
Department of Radiology, Erciyes University Medical Faculty, Kayseri, Turkey.
出版信息
Pol J Radiol. 2017 Apr 13;82:209-215. doi: 10.12659/PJR.899984. eCollection 2017.
BACKGROUND
To evaluate the value of diffusion-weighted imaging (DWI) for distinguishing between benign and malignant renal masses.
MATERIAL/METHODS: Seventy-five patients with 75 unilateral renal lesions were included, and 75 normal contralateral kidneys served as controls. The lesions were categorized into four groups as malignant cystic, malignant solid, benign cystic and benign solid. The apparent diffusion coefficients (ADCs) were evaluated for two different b values (b=600 s/mm and b=1000 s/mm). Receiving operating characteristic analysis was performed to identify threshold ADCs.
RESULTS
Sensitivity and specificity were 67% and 77% (p=0.003) at the cutoff value of 1.5 for b=600 s/mm, and 79% and 62% (p=0.004) at the cutoff value of 1.99 for b=1000 s/mm as regards the differentiation between solid benign and malignant renal lesions. Sensitivity and specificity were 78% and 79% (p=0.001) at the cutoff value of 3.1 for b=600 s/mm, and 86% and 61% (p=0.003) at the cutoff value of 2.9 for b=1000 s/mm as regrads the differentiation between benign and malignant cystic renal lesions.
CONCLUSIONS
DWI can be an effective diagnostic method for distinguishing between benign and malignant renal masses.
背景
评估扩散加权成像（DWI）在鉴别肾良恶性肿块中的价值。
材料/方法：纳入75例患有75个单侧肾病变的患者，75个对侧正常肾脏作为对照。病变分为恶性囊性、恶性实性、良性囊性和良性实性四组。针对两个不同的b值（b = 600 s/mm²和b = 1000 s/mm²）评估表观扩散系数（ADC）。进行接受操作特征分析以确定ADC阈值。
结果
对于实性肾良性和恶性病变的鉴别，当b = 600 s/mm²时，在截断值为1.5时敏感性和特异性分别为67%和77%（p = 0.003），当b = 1000 s/mm²时，在截断值为1.99时敏感性和特异性分别为79%和62%（p = 0.004）。对于囊性肾良性和恶性病变的鉴别，当b = 600 s/mm²时，在截断值为3.1时敏感性和特异性分别为78%和79%（p = 0.001），当b = 1000 s/mm²时，在截断值为2.9时敏感性和特异性分别为86%和61%（p = 0.003）。
结论
DWI可作为鉴别肾良恶性肿块的有效诊断方法。
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