Jensen R E, Berndt W O
University of Nebraska Medical Center, Department of Pharmacology, College of Medicine, Omaha 68105.
Life Sci. 1988;43(18):1473-8. doi: 10.1016/0024-3205(88)90259-7.
Alpha adrenergic receptors are identified on basolateral plasma membranes derived from proximal tubular epithelial cells. The density of alpha 2 receptors was over two-fold greater than alpha 1 receptors. The basolateral membranes were devoid of beta receptors. These results support previous demonstrations of alpha adrenergic receptors in rat renal cortex and concur with studies which suggest a limited presence of beta receptors on rat proximal tubules.
在源自近端肾小管上皮细胞的基底外侧质膜上鉴定出α肾上腺素能受体。α2受体的密度比α1受体高出两倍多。基底外侧膜没有β受体。这些结果支持了先前在大鼠肾皮质中对α肾上腺素能受体的证明，并与表明大鼠近端小管上β受体存在有限的研究结果一致。
