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脑积水消退后出现的大泌乳素瘤。

Macroprolactinoma appearing after resolution of hydrocephalus.

作者信息

Bruno Oscar D, Pisani Ricardo Fernández, Isaac Gabriel, Basso Armando

机构信息

Division of Endocrinology.

Fundacion de Endocrinologia.

出版信息

Endocrinol Diabetes Metab Case Rep. 2017 Apr 19;2017. doi: 10.1530/EDM-16-0157. eCollection 2017.

DOI:10.1530/EDM-16-0157
PMID:28469923
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5409935/
Abstract

SUMMARY

The role of mechanical forces influencing the growth of a pituitary adenoma is poorly understood. In this paper we report the case of a young man with hyperprolactinaemia and an empty sella secondary to hydrocephalia, who developed a macroprolactinoma following the relief of high intraventricular pressure.

LEARNING POINTS

The volume of a pituitary tumour may be influenced not only by molecular but also by local mechanical factors.Intratumoural pressure, resistance of the sellar diaphragm and intracranial liquid pressure may play a role in the final size of a pituitary adenoma.The presence of hydrocephalus may hide a pituitary macroadenoma.

摘要

摘要

机械力对垂体腺瘤生长的影响尚不清楚。本文报告了一名年轻男性病例，该患者因脑积水继发高泌乳素血症和空蝶鞍，在高颅内压缓解后发展为大泌乳素瘤。

学习要点

垂体肿瘤的体积不仅可能受分子因素影响，还可能受局部机械因素影响。肿瘤内压力、鞍隔阻力和颅内液体压力可能对垂体腺瘤的最终大小起作用。脑积水的存在可能掩盖垂体大腺瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/76e1344bf1dd/edmcr-2017-160157-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/8460fccc1ff3/edmcr-2017-160157-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/b62b32c0f697/edmcr-2017-160157-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/3db64228cf51/edmcr-2017-160157-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/76e1344bf1dd/edmcr-2017-160157-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/8460fccc1ff3/edmcr-2017-160157-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/b62b32c0f697/edmcr-2017-160157-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/3db64228cf51/edmcr-2017-160157-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c20/5409935/76e1344bf1dd/edmcr-2017-160157-g004.jpg

相似文献

1
Macroprolactinoma appearing after resolution of hydrocephalus.脑积水消退后出现的大泌乳素瘤。
Endocrinol Diabetes Metab Case Rep. 2017 Apr 19;2017. doi: 10.1530/EDM-16-0157. eCollection 2017.
2
Growth hormone deficiency, secondary hypothyroidism, and empty sella following treatment of childhood macroprolactinoma.儿童大泌乳素瘤治疗后出现生长激素缺乏、继发性甲状腺功能减退和空蝶鞍。
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Resolution of macroprolactinoma-induced symptomatic hydrocephalus following cabergoline therapy.
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[Reversible primary empty sella. Case report].[可逆性原发性空蝶鞍。病例报告]
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The empty sella. A reappraisal of etiology and pathogenesis.空蝶鞍。病因与发病机制的重新评估。
Acta Neurol Scand Suppl. 1990;130:1-25.
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Growth hormone-secreting pituitary adenoma confined to the sphenoid sinus associated with a normal-sized empty sella.局限于蝶窦的生长激素分泌型垂体腺瘤，伴有正常大小的空蝶鞍。
J Clin Neurosci. 2002 Mar;9(2):196-9. doi: 10.1054/jocn.2001.0988.
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Adult hydrocephalus and the empty sella.
Acta Neurol Scand. 1984 Sep;70(3):201-3. doi: 10.1111/j.1600-0404.1984.tb00820.x.
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[Secondary empty sella syndrome: report of three cases and review of the literature].[继发性空蝶鞍综合征：三例报告及文献复习]
No Shinkei Geka. 1982 Nov;10(11):1189-94.
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Combined trans-sphenoidal and simultaneous trans-ventricular-endoscopic decompression of a giant pituitary adenoma: case report.经蝶窦联合同期经脑室-内镜减压治疗巨大垂体腺瘤：病例报告
Acta Neurochir (Wien). 2009 Jul;151(7):843-7; discussion 847. doi: 10.1007/s00701-009-0336-z. Epub 2009 Apr 28.
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Empty sella following spontaneous resolution of a pituitary macroadenoma.垂体大腺瘤自发消退后的空蝶鞍。
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本文引用的文献

1
Growth patterns of pituitary adenomas and histopathological correlates.垂体腺瘤的生长模式及组织病理学相关性。
J Clin Endocrinol Metab. 2014 Apr;99(4):1330-8. doi: 10.1210/jc.2013-3054. Epub 2014 Jan 1.
2
Factors determining the clinical significance of an "empty" sella turcica.影响空蝶鞍临床意义的因素。
AJR Am J Roentgenol. 2013 May;200(5):1125-31. doi: 10.2214/AJR.12.9013.
3
Microsurgical anatomy of the diaphragma sellae and its role in directing the pattern of growth of pituitary adenomas.鞍膈的显微外科解剖及其在指导垂体腺瘤生长模式中的作用。
Neurosurgery. 2008 Mar;62(3):717-23; discussion 717-23. doi: 10.1227/01.neu.0000317321.79106.37.
4
Advances in the treatment of prolactinomas.催乳素瘤治疗的进展
Endocr Rev. 2006 Aug;27(5):485-534. doi: 10.1210/er.2005-9998. Epub 2006 May 26.
5
Monitoring and interpretation of intracranial pressure.颅内压的监测与解读
J Neurol Neurosurg Psychiatry. 2004 Jun;75(6):813-21. doi: 10.1136/jnnp.2003.033126.
6
Intrasellar pituitary tissue pressure, tumour size and endocrine status--an international comparison in 107 patients.鞍内垂体组织压力、肿瘤大小与内分泌状态——107例患者的国际比较
Br J Neurosurg. 1994;8(3):313-8. doi: 10.3109/02688699409029619.