Department of Haematology, Oslo University Hospital, Oslo, Norway.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Semin Thromb Hemost. 2017 Jul;43(5):500-504. doi: 10.1055/s-0037-1599142. Epub 2017 May 3.
Postthrombotic syndrome (PTS) is the most common long-term complication after deep vein thrombosis (DVT) and is associated with reduced quality of life. There is no single objective test to diagnose the presence of PTS and it is usually diagnosed on the basis of typical symptoms and signs in a limb previously affected by DVT. Scoring systems for PTS are primarily developed as research tools, but could possibly also be useful in the clinical setting. A main advantage of a good scoring system is standardization of the diagnostic process. An optimal scoring system should be both sensitive and specific for PTS, but this has been difficult to achieve because the symptoms and signs of PTS can be similar to other conditions leading to complaints in the lower limb. In an effort to standardize the definition of PTS, in 2009, the International Society on Thrombosis and Haemostasis Subcommittee on Control of Anticoagulation reviewed available scales and recommended use of the Villalta scale as the most appropriate measure to diagnose and grade the severity of PTS. The aim of this article is to review the existing scoring systems for PTS and to present our view on the advantages and disadvantages of these diagnostic tools.
血栓后综合征（PTS）是深静脉血栓形成（DVT）后最常见的长期并发症，与生活质量下降有关。目前尚无单一的客观检查用于诊断 PTS，通常根据先前患有 DVT 的肢体的典型症状和体征进行诊断。PTS 的评分系统主要作为研究工具开发，但在临床环境中也可能有用。一个好的评分系统的主要优点是诊断过程的标准化。一个理想的评分系统应该对 PTS 具有敏感性和特异性，但这很难实现，因为 PTS 的症状和体征可能与导致下肢不适的其他疾病相似。为了标准化 PTS 的定义，2009 年，国际血栓形成和止血学会抗凝控制小组委员会审查了现有的量表，并建议使用 Villalta 量表作为诊断和分级 PTS 严重程度的最适当措施。本文的目的是回顾现有的 PTS 评分系统，并就这些诊断工具的优缺点提出我们的看法。
