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传统骨肉瘤散发性和延迟性转移后的长期生存:一例报告。

Long-term survival after sporadic and delayed metastases of conventional osteosarcoma: A case report.

作者信息

Kubo Tadahiko, Furuta Taisuke, Johan Muhammad P, Yoshizuka Masaaki, Ochi Mitsuo, Adachi Nobuo

机构信息

Department of Orthopaedic Surgery, Integrated Health Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

出版信息

Medicine (Baltimore). 2017 May;96(18):e6824. doi: 10.1097/MD.0000000000006824.

Abstract

Histologically conventional osteosarcoma, once metastasized to the lung, generally causes a rapid and fatal outcome. Osteosarcoma metastasis to the gastrointestinal tract is extremely rare.We report herein a case of osteoblastic osteosarcoma with exceptionally unique features: sporadic lung metastases and delayed metastases to the stomach and the jejunum with long-term survival. She received multiple operations and chemotherapies, but consequently died of peritoneal dissemination. A review of the literature on osteosarcoma metastasis to the gastrointestinal tract is presented.This patient was very unusual in terms of a long-term survival and metastatic sites, suggesting the importance of vigilance and thorough follow-up for patients with conventional osteosarcoma.

摘要

组织学上的传统骨肉瘤一旦转移至肺部,通常会导致迅速且致命的后果。骨肉瘤转移至胃肠道极为罕见。我们在此报告一例具有异常独特特征的成骨性骨肉瘤病例:散发性肺转移以及延迟转移至胃和空肠且长期存活。她接受了多次手术和化疗,但最终死于腹膜播散。本文对骨肉瘤转移至胃肠道的文献进行了综述。该患者在长期存活和转移部位方面非常特殊,提示对于传统骨肉瘤患者保持警惕并进行全面随访的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cea8/5419932/52c35515c712/medi-96-e6824-g001.jpg

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