Sakamoto Yuichiro, Yokouchi Masahiro, Nagano Satoshi, Shimada Hirofumi, Nakamura Shunsuke, Setoguchi Takao, Kawamura Ichiro, Ishidou Yasuhiro, Tanimoto Akihide, Komiya Setsuro
Department of Orthopedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.
World J Surg Oncol. 2014 Jun 4;12:176. doi: 10.1186/1477-7819-12-176.
Metastasis of a primary osteosarcoma to the muscles is extremely rare. As there have been few reported cases, the necessity of surgical treatment for such metastatic lesions remains controversial. We present the case of a primary osteosarcoma with development of a solitary metastasis to the trapezius muscle during chemotherapy for pulmonary metastasis. The patient was a 51-year-old man diagnosed with osteosarcoma of the right tibia. After undergoing chemotherapy and femoral amputation, he developed pulmonary metastasis. Chemotherapy was reinitiated, however, after approximately 1 year a palpable tumor was identified in the patient's right shoulder. This tumor grew and was associated with pain in the right shoulder. It was surgically removed 3 years after the re-initiation of chemotherapy. The pathological diagnosis was osteosarcoma with metastasis to the trapezius muscle. Although the patient died of respiratory failure due to pulmonary metastasis 14 months after resection of the metastatic lesion in the trapezius muscle, no new extrapulmonary metastasis was observed after the resection.
原发性骨肉瘤转移至肌肉极为罕见。由于报道的病例很少,对于此类转移性病变进行手术治疗的必要性仍存在争议。我们报告一例原发性骨肉瘤病例,该患者在针对肺转移进行化疗期间出现了孤立性转移至斜方肌的情况。患者为一名51岁男性,被诊断为右胫骨骨肉瘤。在接受化疗和股骨截肢术后,他出现了肺转移。随后重新开始化疗,然而,大约1年后在患者右肩部发现了一个可触及的肿瘤。这个肿瘤不断生长,并伴有右肩部疼痛。在重新开始化疗3年后将其手术切除。病理诊断为骨肉瘤伴转移至斜方肌。尽管患者在斜方肌转移性病变切除术后14个月因肺转移死于呼吸衰竭,但切除术后未观察到新的肺外转移。