Thein P, Brown K
Bayer AG, Geschäftsbereich Veterinärmedizin, Forschung und Entwicklung Biologie, Leverkusen.
Tierarztl Prax. 1988;16(3):295-302.
Infections with EHV1 can lead to manifestation at the CNS of horses followed by encephalomyelitis and "equine stroke". Horse experiments could confirm the clinical picture and gave links to the potential pathogenesis of the disease. We also have been in the position to isolate and characterize an EHV4 virus out of the brain of a horse with CNS disorders. The two viruses carry different biological properties which obviously dominate the pathogenesis. These properties as well as experimental and field cases are described and different diagnostic tests are discussed.
感染EHV1可导致马的中枢神经系统出现症状，随后引发脑脊髓炎和“马中风”。马匹实验能够证实临床症状，并揭示该疾病潜在的发病机制。我们还成功地从一匹患有中枢神经系统疾病的马的大脑中分离并鉴定出一种EHV4病毒。这两种病毒具有不同的生物学特性，显然这些特性主导了发病机制。本文描述了这些特性以及实验和实际病例，并讨论了不同的诊断测试。
