Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital at Linkou, Institute for Radiological Research, College of Medicine, Chang Gung University, (333), Taoyuan, Taiwan.
Department of Public Health and Center of Biostatistics, College of Medicine, Chang Gung University, (333), Taoyuan, Taiwan.
Sci Rep. 2017 May 4;7(1):1515. doi: 10.1038/s41598-017-01679-3.
We evaluated the correlation of the left main coronary bifurcating angle (LCBA) with the severity of coronary atherosclerosis, risk factors of coronary artery disease (CAD) and the feasibility of measuring the LBCA using the axial plane. Coronary Computed tomography angiographies (CTAs) of 313 patients between Nov. 2006 and Oct. 2013 were reviewed and separated into three groups. Group I (211 patients) had significant stenosis (≥50%) of the left anterior descending coronary artery (LAD) and/or left circumflex coronary artery (LCX). Group II (62 subjects) had atherosclerosis without significant stenosis. Group III (40 subjects) had unremarkable coronary CTAs. Both Group I and II patients received conventional catheter angiography to confirm the severities of coronary stenoses. Significant differences were found among the groups with respect to risk factors, such as male gender, hypertension and body mass index. Axial plane measurement was feasible in most patients (82.1%), without significant differences among the groups. The mean LCBA was 84.7° among all patients, and significantly differed among groups I, II and III (87.34°, 81.16° and 75.53°, P < 0.001). The LCBA of group I was significantly higher than group III (P < 0.001) in univariate analysis, but insignificant in multivariate analysis (P = 0.064).
我们评估了左主干冠状动脉分叉角(LCBA)与冠状动脉粥样硬化严重程度、冠心病危险因素以及在轴面测量 LBCA 的可行性之间的相关性。回顾了 2006 年 11 月至 2013 年 10 月间 313 例患者的冠状动脉计算机断层血管造影(CTA),并将其分为三组。组 I(211 例)有左前降支(LAD)和/或左旋支(LCX)的狭窄(≥50%)。组 II(62 例)有动脉粥样硬化但无明显狭窄。组 III(40 例)冠状动脉 CTA 无明显异常。I 组和 II 组的患者均接受了常规导管血管造影以确认冠状动脉狭窄的严重程度。三组间的危险因素(如性别、高血压和体重指数)存在显著差异。轴面测量在大多数患者中是可行的(82.1%),但各组间无显著差异。所有患者的平均 LCBA 为 84.7°,组 I、组 II 和组 III 间有显著差异(87.34°、81.16°和 75.53°,P<0.001)。单因素分析显示,I 组的 LCBA 明显高于 III 组(P<0.001),但多因素分析则无显著差异(P=0.064)。