Geerlings-Batt Jade, Gupta Ashu, Sun Zhonghua
Discipline of Medical Radiation Science, Curtin Medical School, Curtin University, Perth, WA 6845, Australia.
Medical Imaging Department, Fiona Stanley Hospital, Perth, WA 6150, Australia.
J Clin Med. 2023 Jan 29;12(3):1051. doi: 10.3390/jcm12031051.
At the level of the left coronary artery tree, there is evidence showing an association between bifurcation angle and coronary artery disease (CAD), and this motivated us to explore similar associations at the level of the right coronary artery (RCA). The purpose of this study was to determine whether there is a relationship between RCA-aorta angle and CAD and age, sex, body mass index, smoking status, hypertension, and high blood cholesterol. The coronary computed tomography angiography datasets and CAD risk factor checklists of 250 patients were retrospectively reviewed, with RCA-aorta angles measured via multiplanar reformation images. Independent -tests were used to compare mean RCA-aorta angle measurements between groups, correlations between continuous variables were assessed using Pearson and Spearman correlations, and a general linear model was used to adjust for potentially confounding variables. Coronary angle measurements were conducted by two independent assessors with very strong intraclass correlation (r=0.999, p<0.001). A significantly smaller mean RCA-aorta angle was observed in the CAD group (79.07 ± 24.88°) compared to the normal group (92.08 ± 19.51°, p=0.001), in smokers (76.63 ± 22.94°) compared to non-smokers (85.25 ± 23.84°, p=0.016), and a narrow RCA-aorta angle was negatively correlated with BMI (r=-0.174, p=0.010). This study suggests a relationship between narrow RCA-aorta angles and CAD, smoking, and increasing BMI.
在左冠状动脉树层面，有证据表明分叉角度与冠状动脉疾病（CAD）之间存在关联，这促使我们在右冠状动脉（RCA）层面探索类似的关联。本研究的目的是确定RCA与主动脉夹角是否与CAD以及年龄、性别、体重指数、吸烟状况、高血压和高胆固醇血症有关。回顾性分析了250例患者的冠状动脉计算机断层扫描血管造影数据集和CAD危险因素清单，并通过多平面重组图像测量RCA与主动脉夹角。采用独立样本t检验比较组间平均RCA与主动脉夹角测量值，使用Pearson和Spearman相关性评估连续变量之间的相关性，并使用一般线性模型调整潜在的混杂变量。冠状动脉角度测量由两名独立评估者进行，组内相关性非常强（r=0.999，p<0.001）。与正常组（92.08±19.51°，p=0.001）相比，CAD组的平均RCA与主动脉夹角明显更小（79.07±24.88°）；与非吸烟者（85.25±23.84°，p=0.016）相比，吸烟者的平均RCA与主动脉夹角更小（76.63±22.94°），且RCA与主动脉夹角变窄与体重指数呈负相关（r=-0.174，p=0.010）。本研究表明，RCA与主动脉夹角变窄与CAD、吸烟和体重指数增加之间存在关联。
