居住在泰国和肯尼亚的索马里、缅甸及苗族难民中组织胞浆菌病的血清阳性率
Seroprevalence of Histoplasmosis in Somali, Burmese, and Hmong Refugees Residing in Thailand and Kenya.
作者信息
Bahr Nathan C, Lee Deborah, Stauffer William M, Durkin Michelle, Cetron Martin S, Wheat L Joseph, Boulware David R
机构信息
Division of Infectious Diseases, Department of Medicine, University of Kansas, 3901 Rainbow Boulevard, MS 1028, Kansas City, KS, 66160, USA.
Division of Infectious Disease and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
出版信息
J Immigr Minor Health. 2018 Apr;20(2):334-338. doi: 10.1007/s10903-017-0595-3.
Histoplasmosis is known to be endemic to the Midwestern United States, but cases have been reported throughout much of the world. Somali, Hmong, and Burmese (ethnically Karen) persons make up some of the largest refugee populations coming the United States in recent years. Yet, information about risk of Histoplasma capsulatum infection amongst these populations is limited. This study used the CDC Migrant Serum Bank to test ~100 samples from each of Somali, Burmese, and Hmong U.S.-bound refugees. Samples were tested by enzyme immunoassay for Histoplasma capsulatum IgG. Overall 1% (2/299) of refugee serum samples were positive for H. capsulatum IgG. One of 99 samples obtained from Hmong refugees was positive, and the other positive sample came from among 100 Burmese refugee samples. H capsulatum IgG positivity was detected at low levels in Hmong and Burmese refugees. No IgG positivity was detected among 100 Somali refugees.
组织胞浆菌病在美国中西部地区呈地方性流行，但世界各地均有病例报告。索马里人、苗族人和缅甸人（克伦族）是近年来进入美国的一些最大难民群体。然而，关于这些人群中荚膜组织胞浆菌感染风险的信息有限。本研究利用美国疾病控制与预防中心的移民血清库，对来自索马里、缅甸和苗族的约100名赴美难民的样本进行检测。采用酶免疫法检测样本中的荚膜组织胞浆菌IgG。总体而言，1%（2/299）的难民血清样本荚膜组织胞浆菌IgG呈阳性。从苗族难民中获取的99份样本中有1份呈阳性，另一份阳性样本来自100份缅甸难民样本。在苗族和缅甸难民中检测到低水平的荚膜组织胞浆菌IgG阳性。在100名索马里难民中未检测到IgG阳性。
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