Bos C A
Department of Demography, State University Groningen, The Netherlands.
Vaccine. 1988 Aug;6(4):309-14. doi: 10.1016/0264-410x(88)90176-4.
The apparently increasing evidence of herpes simplex virus infections of the genital tract has focused attention on preventing the infection by vaccination. Herpes genitalis is not, however, the most quantitatively important clinical manifestation of herpes simplex virus infections. Because 41% of the hospitalized patients are younger than 20 years, vaccination of birth cohorts would be more favourable. In this paper the financial benefits of a hypothetical herpes simplex virus vaccination were calculated with the use of a population projection model. For the Netherlands, if the price of the hypothetical herpes simplex virus vaccine equals the cost price of the mumps component of the combined mumps-measles-rubella vaccine, the herpes vaccine would be profitable within 8 years.
生殖道单纯疱疹病毒感染明显增多的证据，已将预防感染的注意力集中在疫苗接种上。然而，生殖器疱疹并非单纯疱疹病毒感染在数量上最重要的临床表现。由于41%的住院患者年龄小于20岁，对出生队列进行疫苗接种会更有利。在本文中，使用人口预测模型计算了一种假设的单纯疱疹病毒疫苗接种的经济效益。对于荷兰而言，如果假设的单纯疱疹病毒疫苗价格等于腮腺炎-麻疹-风疹联合疫苗中腮腺炎成分的成本价，那么该疱疹疫苗将在8年内实现盈利。
