Wick M R, Swanson P E, Kaye V N, Pittelkow M R
Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis.
Am J Dermatopathol. 1987 Apr;9(2):90-8. doi: 10.1097/00000372-198704000-00002.
We herein report two cases of sweat gland carcinoma that arose in association with eccrine spiradenoma. These lesions presented as enlarging masses that previously had been stable for many years. One produced widespread metastasis and death 5 months after diagnosis. Immunohistochemical studies demonstrated an antigenic relationship between the benign and malignant components of sweat gland carcinoma ex eccrine spiradenoma, but ultrastructural analyses showed a paucity of specialized differentiation. This neoplasm appears to display a range of microscopic appearances and has proven fatal in 20% of reported cases.
我们在此报告两例与小汗腺螺旋腺瘤相关的汗腺癌病例。这些病变表现为逐渐增大的肿块，此前多年一直稳定。其中一例在诊断后5个月发生广泛转移并死亡。免疫组织化学研究表明，汗腺癌外小汗腺螺旋腺瘤的良性和恶性成分之间存在抗原关系，但超微结构分析显示缺乏特殊分化。这种肿瘤似乎呈现出一系列微观表现，在已报道的病例中有20%被证明是致命的。
